node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ADAT2 | ADAT3 | ENSSSCP00000072121 | ENSSSCP00000033184 | Adenosine deaminase tRNA specific 2. | Putative inactive tRNA-specific adenosine deaminase-like protein 3 isoform 1. | 0.995 |
ADAT2 | HDDC2 | ENSSSCP00000072121 | ENSSSCP00000004562 | Adenosine deaminase tRNA specific 2. | HD domain-containing protein 2. | 0.661 |
ADAT2 | MTAP | ENSSSCP00000072121 | ENSSSCP00000005522 | Adenosine deaminase tRNA specific 2. | S-methyl-5'-thioadenosine phosphorylase; Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates. | 0.555 |
ADAT2 | PNP | ENSSSCP00000072121 | ENSSSCP00000002333 | Adenosine deaminase tRNA specific 2. | Purine nucleoside phosphorylase; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate. | 0.555 |
ADAT3 | ADAT2 | ENSSSCP00000033184 | ENSSSCP00000072121 | Putative inactive tRNA-specific adenosine deaminase-like protein 3 isoform 1. | Adenosine deaminase tRNA specific 2. | 0.995 |
ADAT3 | HDDC2 | ENSSSCP00000033184 | ENSSSCP00000004562 | Putative inactive tRNA-specific adenosine deaminase-like protein 3 isoform 1. | HD domain-containing protein 2. | 0.661 |
ADAT3 | MTAP | ENSSSCP00000033184 | ENSSSCP00000005522 | Putative inactive tRNA-specific adenosine deaminase-like protein 3 isoform 1. | S-methyl-5'-thioadenosine phosphorylase; Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates. | 0.555 |
ADAT3 | PNP | ENSSSCP00000033184 | ENSSSCP00000002333 | Putative inactive tRNA-specific adenosine deaminase-like protein 3 isoform 1. | Purine nucleoside phosphorylase; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate. | 0.555 |
ADAT3 | SMUG1 | ENSSSCP00000033184 | ENSSSCP00000024249 | Putative inactive tRNA-specific adenosine deaminase-like protein 3 isoform 1. | Single-strand-selective monofunctional uracil-DNA glycosylase 1. | 0.870 |
DALRD3 | HDDC2 | ENSSSCP00000012123 | ENSSSCP00000004562 | DALR anticodon-binding domain-containing protein 3 isoform 1. | HD domain-containing protein 2. | 0.538 |
DALRD3 | MTAP | ENSSSCP00000012123 | ENSSSCP00000005522 | DALR anticodon-binding domain-containing protein 3 isoform 1. | S-methyl-5'-thioadenosine phosphorylase; Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates. | 0.487 |
DALRD3 | PNP | ENSSSCP00000012123 | ENSSSCP00000002333 | DALR anticodon-binding domain-containing protein 3 isoform 1. | Purine nucleoside phosphorylase; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate. | 0.502 |
HDDC2 | ADAT2 | ENSSSCP00000004562 | ENSSSCP00000072121 | HD domain-containing protein 2. | Adenosine deaminase tRNA specific 2. | 0.661 |
HDDC2 | ADAT3 | ENSSSCP00000004562 | ENSSSCP00000033184 | HD domain-containing protein 2. | Putative inactive tRNA-specific adenosine deaminase-like protein 3 isoform 1. | 0.661 |
HDDC2 | DALRD3 | ENSSSCP00000004562 | ENSSSCP00000012123 | HD domain-containing protein 2. | DALR anticodon-binding domain-containing protein 3 isoform 1. | 0.538 |
HDDC2 | IMPDH1 | ENSSSCP00000004562 | ENSSSCP00000017570 | HD domain-containing protein 2. | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Could also have a single-stranded nucleic acid-binding activity and could play a role in RNA and/or DNA metabolism. It may also have a role in the development of malignancy and the growth progression of some tumors. | 0.538 |
HDDC2 | METTL15 | ENSSSCP00000004562 | ENSSSCP00000072152 | HD domain-containing protein 2. | Methyltransferase like 15. | 0.548 |
HDDC2 | METTL5 | ENSSSCP00000004562 | ENSSSCP00000068023 | HD domain-containing protein 2. | Methyltransferase like 5. | 0.566 |
HDDC2 | MTAP | ENSSSCP00000004562 | ENSSSCP00000005522 | HD domain-containing protein 2. | S-methyl-5'-thioadenosine phosphorylase; Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates. | 0.785 |
HDDC2 | NUDT12 | ENSSSCP00000004562 | ENSSSCP00000015090 | HD domain-containing protein 2. | Nudix hydrolase 12. | 0.768 |