node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
CS | DDO | ENSSSCP00000056310 | ENSSSCP00000044106 | Citrate synthase, mitochondrial; Belongs to the citrate synthase family. | D-aspartate oxidase; Selectively catalyzes the oxidative deamination of D- aspartate and its N-methylated derivative, N-methyl D-aspartate. Belongs to the DAMOX/DASOX family. | 0.859 |
CS | GOT1 | ENSSSCP00000056310 | ENSSSCP00000011226 | Citrate synthase, mitochondrial; Belongs to the citrate synthase family. | Aspartate aminotransferase, cytoplasmic; Biosynthesis of L-glutamate from L-aspartate or L-cysteine. Important regulator of levels of glutamate, the major excitatory neurotransmitter of the vertebrate central nervous system. Acts as a scavenger of glutamate in brain neuroprotection. The aspartate aminotransferase activity is involved in hepatic glucose synthesis during development and in adipocyte glyceroneogenesis. Using L-cysteine as substrate, regulates levels of mercaptopyruvate, an important source of hydrogen sulfide. Mercaptopyruvate is converted into H(2)S via the action of 3-m [...] | 0.892 |
CS | GOT1L1 | ENSSSCP00000056310 | ENSSSCP00000043472 | Citrate synthase, mitochondrial; Belongs to the citrate synthase family. | Glutamic-oxaloacetic transaminase 1 like 1. | 0.879 |
CS | GOT2 | ENSSSCP00000056310 | ENSSSCP00000055842 | Citrate synthase, mitochondrial; Belongs to the citrate synthase family. | Aspartate aminotransferase, mitochondrial; Catalyzes the irreversible transamination of the L-tryptophan metabolite L-kynurenine to form kynurenic acid (KA). Plays a key role in amino acid metabolism. Important for metabolite exchange between mitochondria and cytosol. Facilitates cellular uptake of long-chain free fatty acids (By similarity). | 0.932 |
CS | IDH1 | ENSSSCP00000056310 | ENSSSCP00000022058 | Citrate synthase, mitochondrial; Belongs to the citrate synthase family. | Isocitrate dehydrogenase [NADP]; Belongs to the isocitrate and isopropylmalate dehydrogenases family. | 0.966 |
CS | IDH2 | ENSSSCP00000056310 | ENSSSCP00000036736 | Citrate synthase, mitochondrial; Belongs to the citrate synthase family. | Isocitrate dehydrogenase [NADP], mitochondrial; Plays a role in intermediary metabolism and energy production. It may tightly associate or interact with the pyruvate dehydrogenase complex. | 0.971 |
CS | IL4I1 | ENSSSCP00000056310 | ENSSSCP00000003464 | Citrate synthase, mitochondrial; Belongs to the citrate synthase family. | Amine oxidase. | 0.812 |
CS | LOC100525099 | ENSSSCP00000056310 | ENSSSCP00000036380 | Citrate synthase, mitochondrial; Belongs to the citrate synthase family. | Amine oxidase. | 0.818 |
CS | NIT2 | ENSSSCP00000056310 | ENSSSCP00000012751 | Citrate synthase, mitochondrial; Belongs to the citrate synthase family. | Nitrilase family member 2. | 0.801 |
CS | OGDHL | ENSSSCP00000056310 | ENSSSCP00000036125 | Citrate synthase, mitochondrial; Belongs to the citrate synthase family. | Oxoglutarate dehydrogenase like. | 0.788 |
DDO | CS | ENSSSCP00000044106 | ENSSSCP00000056310 | D-aspartate oxidase; Selectively catalyzes the oxidative deamination of D- aspartate and its N-methylated derivative, N-methyl D-aspartate. Belongs to the DAMOX/DASOX family. | Citrate synthase, mitochondrial; Belongs to the citrate synthase family. | 0.859 |
DDO | GOT1 | ENSSSCP00000044106 | ENSSSCP00000011226 | D-aspartate oxidase; Selectively catalyzes the oxidative deamination of D- aspartate and its N-methylated derivative, N-methyl D-aspartate. Belongs to the DAMOX/DASOX family. | Aspartate aminotransferase, cytoplasmic; Biosynthesis of L-glutamate from L-aspartate or L-cysteine. Important regulator of levels of glutamate, the major excitatory neurotransmitter of the vertebrate central nervous system. Acts as a scavenger of glutamate in brain neuroprotection. The aspartate aminotransferase activity is involved in hepatic glucose synthesis during development and in adipocyte glyceroneogenesis. Using L-cysteine as substrate, regulates levels of mercaptopyruvate, an important source of hydrogen sulfide. Mercaptopyruvate is converted into H(2)S via the action of 3-m [...] | 0.925 |
DDO | GOT1L1 | ENSSSCP00000044106 | ENSSSCP00000043472 | D-aspartate oxidase; Selectively catalyzes the oxidative deamination of D- aspartate and its N-methylated derivative, N-methyl D-aspartate. Belongs to the DAMOX/DASOX family. | Glutamic-oxaloacetic transaminase 1 like 1. | 0.980 |
DDO | GOT2 | ENSSSCP00000044106 | ENSSSCP00000055842 | D-aspartate oxidase; Selectively catalyzes the oxidative deamination of D- aspartate and its N-methylated derivative, N-methyl D-aspartate. Belongs to the DAMOX/DASOX family. | Aspartate aminotransferase, mitochondrial; Catalyzes the irreversible transamination of the L-tryptophan metabolite L-kynurenine to form kynurenic acid (KA). Plays a key role in amino acid metabolism. Important for metabolite exchange between mitochondria and cytosol. Facilitates cellular uptake of long-chain free fatty acids (By similarity). | 0.919 |
DDO | IDH1 | ENSSSCP00000044106 | ENSSSCP00000022058 | D-aspartate oxidase; Selectively catalyzes the oxidative deamination of D- aspartate and its N-methylated derivative, N-methyl D-aspartate. Belongs to the DAMOX/DASOX family. | Isocitrate dehydrogenase [NADP]; Belongs to the isocitrate and isopropylmalate dehydrogenases family. | 0.824 |
DDO | IDH2 | ENSSSCP00000044106 | ENSSSCP00000036736 | D-aspartate oxidase; Selectively catalyzes the oxidative deamination of D- aspartate and its N-methylated derivative, N-methyl D-aspartate. Belongs to the DAMOX/DASOX family. | Isocitrate dehydrogenase [NADP], mitochondrial; Plays a role in intermediary metabolism and energy production. It may tightly associate or interact with the pyruvate dehydrogenase complex. | 0.824 |
DDO | IL4I1 | ENSSSCP00000044106 | ENSSSCP00000003464 | D-aspartate oxidase; Selectively catalyzes the oxidative deamination of D- aspartate and its N-methylated derivative, N-methyl D-aspartate. Belongs to the DAMOX/DASOX family. | Amine oxidase. | 0.911 |
DDO | LOC100525099 | ENSSSCP00000044106 | ENSSSCP00000036380 | D-aspartate oxidase; Selectively catalyzes the oxidative deamination of D- aspartate and its N-methylated derivative, N-methyl D-aspartate. Belongs to the DAMOX/DASOX family. | Amine oxidase. | 0.905 |
DDO | NIT2 | ENSSSCP00000044106 | ENSSSCP00000012751 | D-aspartate oxidase; Selectively catalyzes the oxidative deamination of D- aspartate and its N-methylated derivative, N-methyl D-aspartate. Belongs to the DAMOX/DASOX family. | Nitrilase family member 2. | 0.919 |
DDO | OGDHL | ENSSSCP00000044106 | ENSSSCP00000036125 | D-aspartate oxidase; Selectively catalyzes the oxidative deamination of D- aspartate and its N-methylated derivative, N-methyl D-aspartate. Belongs to the DAMOX/DASOX family. | Oxoglutarate dehydrogenase like. | 0.825 |