node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
BAMBI | SMAD3 | ENSSSCP00000011748 | ENSSSCP00000073915 | BMP and activin membrane-bound inhibitor homolog; Negatively regulates TGF-beta signaling. Belongs to the BAMBI family. | Mothers against decapentaplegic homolog. | 0.422 |
BAMBI | SMAD6 | ENSSSCP00000011748 | ENSSSCP00000005325 | BMP and activin membrane-bound inhibitor homolog; Negatively regulates TGF-beta signaling. Belongs to the BAMBI family. | Mothers against decapentaplegic homolog. | 0.530 |
BAMBI | SMAD7 | ENSSSCP00000011748 | ENSSSCP00000004862 | BMP and activin membrane-bound inhibitor homolog; Negatively regulates TGF-beta signaling. Belongs to the BAMBI family. | Mothers against decapentaplegic homolog. | 0.939 |
BAMBI | TGFBR1 | ENSSSCP00000011748 | ENSSSCP00000030910 | BMP and activin membrane-bound inhibitor homolog; Negatively regulates TGF-beta signaling. Belongs to the BAMBI family. | TGF-beta receptor type-1; Transmembrane serine/threonine kinase forming with the TGF- beta type II serine/threonine kinase receptor, TGFBR2, the non- promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinog [...] | 0.936 |
BAMBI | TGFBR2 | ENSSSCP00000011748 | ENSSSCP00000028622 | BMP and activin membrane-bound inhibitor homolog; Negatively regulates TGF-beta signaling. Belongs to the BAMBI family. | TGF-beta receptor type-2; Transmembrane serine/threonine kinase forming with the TGF- beta type I serine/threonine kinase receptor, TGFBR1, the non- promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinoge [...] | 0.652 |
RNF111 | SMAD3 | ENSSSCP00000051514 | ENSSSCP00000073915 | Ring finger protein 111. | Mothers against decapentaplegic homolog. | 0.458 |
RNF111 | SMAD6 | ENSSSCP00000051514 | ENSSSCP00000005325 | Ring finger protein 111. | Mothers against decapentaplegic homolog. | 0.478 |
RNF111 | SMAD7 | ENSSSCP00000051514 | ENSSSCP00000004862 | Ring finger protein 111. | Mothers against decapentaplegic homolog. | 0.962 |
SMAD3 | BAMBI | ENSSSCP00000073915 | ENSSSCP00000011748 | Mothers against decapentaplegic homolog. | BMP and activin membrane-bound inhibitor homolog; Negatively regulates TGF-beta signaling. Belongs to the BAMBI family. | 0.422 |
SMAD3 | RNF111 | ENSSSCP00000073915 | ENSSSCP00000051514 | Mothers against decapentaplegic homolog. | Ring finger protein 111. | 0.458 |
SMAD3 | SMAD5 | ENSSSCP00000073915 | ENSSSCP00000032987 | Mothers against decapentaplegic homolog. | Mothers against decapentaplegic homolog. | 0.794 |
SMAD3 | SMAD6 | ENSSSCP00000073915 | ENSSSCP00000005325 | Mothers against decapentaplegic homolog. | Mothers against decapentaplegic homolog. | 0.930 |
SMAD3 | SMAD7 | ENSSSCP00000073915 | ENSSSCP00000004862 | Mothers against decapentaplegic homolog. | Mothers against decapentaplegic homolog. | 0.944 |
SMAD3 | SMURF1 | ENSSSCP00000073915 | ENSSSCP00000069876 | Mothers against decapentaplegic homolog. | E3 ubiquitin-protein ligase. | 0.710 |
SMAD3 | SMURF2 | ENSSSCP00000073915 | ENSSSCP00000047401 | Mothers against decapentaplegic homolog. | E3 ubiquitin-protein ligase. | 0.773 |
SMAD3 | TGFBR1 | ENSSSCP00000073915 | ENSSSCP00000030910 | Mothers against decapentaplegic homolog. | TGF-beta receptor type-1; Transmembrane serine/threonine kinase forming with the TGF- beta type II serine/threonine kinase receptor, TGFBR2, the non- promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinog [...] | 0.989 |
SMAD3 | TGFBR2 | ENSSSCP00000073915 | ENSSSCP00000028622 | Mothers against decapentaplegic homolog. | TGF-beta receptor type-2; Transmembrane serine/threonine kinase forming with the TGF- beta type I serine/threonine kinase receptor, TGFBR1, the non- promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinoge [...] | 0.979 |
SMAD3 | YAP1 | ENSSSCP00000073915 | ENSSSCP00000033204 | Mothers against decapentaplegic homolog. | Yes associated protein 1. | 0.946 |
SMAD5 | SMAD3 | ENSSSCP00000032987 | ENSSSCP00000073915 | Mothers against decapentaplegic homolog. | Mothers against decapentaplegic homolog. | 0.794 |
SMAD5 | SMAD6 | ENSSSCP00000032987 | ENSSSCP00000005325 | Mothers against decapentaplegic homolog. | Mothers against decapentaplegic homolog. | 0.934 |