Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ERMP1Endoplasmic reticulum metallopeptidase 1. (1000 aa)    
Predicted Functional Partners:
TMEM209
Transmembrane protein 209 isoform X1.
      
 0.766
TASP1
Taspase 1.
   
  
 0.733
MTX1
Metaxin-1; Involved in transport of proteins into the mitochondrion. Essential for embryonic development (By similarity); Belongs to the metaxin family.
      
 0.704
TTYH3
Protein tweety homolog; Probable chloride channel; Belongs to the tweety family.
   
  
 0.682
TMBIM1
Uncharacterized protein; Belongs to the BI1 family.
      
 0.640
GALNT1
Polypeptide N-acetylgalactosaminyltransferase 1 soluble form; Catalyzes the initial reaction in O-linked oligosaccharide biosynthesis, the transfer of an N-acetyl-D-galactosamine residue to a serine or threonine residue on the protein receptor. Has a broad spectrum of substrates for peptides such as EA2, Muc5AC, Muc1a, Muc1b and Muc7 (By similarity).
      
 0.636
UPP2
Uridine phosphorylase; Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1-phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis.
      
 0.627
ANTXR1
ANTXR cell adhesion molecule 1.
    
 
 0.595
KIAA2026
KIAA2026.
      
 0.592
GGCX
Vitamin K-dependent gamma-carboxylase isoform 1.
     
 0.581
Your Current Organism:
Sus scrofa
NCBI taxonomy Id: 9823
Other names: S. scrofa, pig, pigs, swine, wild boar
Server load: low (16%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.