node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
CER1 | WNT8B | ENSSSCP00000033496 | ENSSSCP00000006575 | Cerberus 1, DAN family BMP antagonist. | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. | 0.900 |
FZD1 | LRP5 | ENSSSCP00000043267 | ENSSSCP00000013700 | Frizzled class receptor 1; Belongs to the G-protein coupled receptor Fz/Smo family. | Low-density lipoprotein receptor-related protein; Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalsomes. Belongs to the LDLR family. | 0.975 |
FZD1 | LRP6 | ENSSSCP00000043267 | ENSSSCP00000040912 | Frizzled class receptor 1; Belongs to the G-protein coupled receptor Fz/Smo family. | Low-density lipoprotein receptor-related protein; Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalsomes. Belongs to the LDLR family. | 0.963 |
FZD1 | PORCN | ENSSSCP00000043267 | ENSSSCP00000039178 | Frizzled class receptor 1; Belongs to the G-protein coupled receptor Fz/Smo family. | Protein-serine O-palmitoleoyltransferase porcupine isoform D; Belongs to the membrane-bound acyltransferase family. | 0.463 |
FZD1 | SFRP2 | ENSSSCP00000043267 | ENSSSCP00000009608 | Frizzled class receptor 1; Belongs to the G-protein coupled receptor Fz/Smo family. | Uncharacterized protein. | 0.704 |
FZD1 | WIF1 | ENSSSCP00000043267 | ENSSSCP00000029993 | Frizzled class receptor 1; Belongs to the G-protein coupled receptor Fz/Smo family. | Wnt inhibitory factor 1. | 0.466 |
FZD1 | WNT8B | ENSSSCP00000043267 | ENSSSCP00000006575 | Frizzled class receptor 1; Belongs to the G-protein coupled receptor Fz/Smo family. | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. | 0.826 |
FZD5 | LRP5 | ENSSSCP00000017100 | ENSSSCP00000013700 | Frizzled class receptor 5; Belongs to the G-protein coupled receptor Fz/Smo family. | Low-density lipoprotein receptor-related protein; Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalsomes. Belongs to the LDLR family. | 0.963 |
FZD5 | LRP6 | ENSSSCP00000017100 | ENSSSCP00000040912 | Frizzled class receptor 5; Belongs to the G-protein coupled receptor Fz/Smo family. | Low-density lipoprotein receptor-related protein; Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalsomes. Belongs to the LDLR family. | 0.961 |
FZD5 | PORCN | ENSSSCP00000017100 | ENSSSCP00000039178 | Frizzled class receptor 5; Belongs to the G-protein coupled receptor Fz/Smo family. | Protein-serine O-palmitoleoyltransferase porcupine isoform D; Belongs to the membrane-bound acyltransferase family. | 0.414 |
FZD5 | SFRP2 | ENSSSCP00000017100 | ENSSSCP00000009608 | Frizzled class receptor 5; Belongs to the G-protein coupled receptor Fz/Smo family. | Uncharacterized protein. | 0.684 |
FZD5 | WNT8B | ENSSSCP00000017100 | ENSSSCP00000006575 | Frizzled class receptor 5; Belongs to the G-protein coupled receptor Fz/Smo family. | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. | 0.828 |
GPC3 | WNT8B | ENSSSCP00000030061 | ENSSSCP00000006575 | Glypican-3 isoform 2; Cell surface proteoglycan that bears heparan sulfate. Belongs to the glypican family. | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. | 0.915 |
LRP5 | FZD1 | ENSSSCP00000013700 | ENSSSCP00000043267 | Low-density lipoprotein receptor-related protein; Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalsomes. Belongs to the LDLR family. | Frizzled class receptor 1; Belongs to the G-protein coupled receptor Fz/Smo family. | 0.975 |
LRP5 | FZD5 | ENSSSCP00000013700 | ENSSSCP00000017100 | Low-density lipoprotein receptor-related protein; Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalsomes. Belongs to the LDLR family. | Frizzled class receptor 5; Belongs to the G-protein coupled receptor Fz/Smo family. | 0.963 |
LRP5 | LRP6 | ENSSSCP00000013700 | ENSSSCP00000040912 | Low-density lipoprotein receptor-related protein; Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalsomes. Belongs to the LDLR family. | Low-density lipoprotein receptor-related protein; Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalsomes. Belongs to the LDLR family. | 0.981 |
LRP5 | PORCN | ENSSSCP00000013700 | ENSSSCP00000039178 | Low-density lipoprotein receptor-related protein; Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalsomes. Belongs to the LDLR family. | Protein-serine O-palmitoleoyltransferase porcupine isoform D; Belongs to the membrane-bound acyltransferase family. | 0.469 |
LRP5 | SFRP2 | ENSSSCP00000013700 | ENSSSCP00000009608 | Low-density lipoprotein receptor-related protein; Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalsomes. Belongs to the LDLR family. | Uncharacterized protein. | 0.497 |
LRP5 | WIF1 | ENSSSCP00000013700 | ENSSSCP00000029993 | Low-density lipoprotein receptor-related protein; Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalsomes. Belongs to the LDLR family. | Wnt inhibitory factor 1. | 0.629 |
LRP5 | WNT8B | ENSSSCP00000013700 | ENSSSCP00000006575 | Low-density lipoprotein receptor-related protein; Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalsomes. Belongs to the LDLR family. | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. | 0.858 |