STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MTX1Metaxin-1; Involved in transport of proteins into the mitochondrion. Essential for embryonic development (By similarity); Belongs to the metaxin family. (463 aa)    
Predicted Functional Partners:
SAMM50
SAMM50 sorting and assembly machinery component.
   
 0.980
TOMM40
Translocase of outer mitochondrial membrane 40.
   
 0.901
TOMM22
Uncharacterized protein.
   
 0.861
TOMM40L
Translocase of outer mitochondrial membrane 40 like.
   
 0.858
MTX2
Metaxin-2; Involved in transport of proteins into the mitochondrion.
    
0.834
TOMM7
Mitochondrial import receptor subunit TOM7 homolog; Required for assembly and stability of the TOM complex (By similarity). Positive regulator of PRKN translocation to damaged mitochondria. Acts probably by stabilizing PINK1 on the outer membrane of depolarized mitochondria (By similarity).
    
 0.733
DNAJC11
DnaJ heat shock protein family (Hsp40) member C11.
    
 0.730
TIMM50
Mitochondrial import inner membrane translocase subunit TIM50; Essential component of the TIM23 complex, a complex that mediates the translocation of transit peptide-containing proteins across the mitochondrial inner membrane.
   
  
 0.700
ERMP1
Endoplasmic reticulum metallopeptidase 1.
      
 0.689
TTYH3
Protein tweety homolog; Probable chloride channel; Belongs to the tweety family.
      
 0.689
Your Current Organism:
Sus scrofa
NCBI taxonomy Id: 9823
Other names: S. scrofa, pig, pigs, swine, wild boar
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.