STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
IVLInvolucrin; Part of the insoluble cornified cell envelope (CE) of stratified squamous epithelia. (409 aa)    
Predicted Functional Partners:
SPRP
Cornifin; Cross-linked envelope protein of keratinocytes. It is a keratinocyte protein that first appears in the cell cytosol, but ultimately becomes cross-linked to membrane proteins by transglutaminase. All that results in the formation of an insoluble envelope beneath the plasma membrane; Belongs to the cornifin (SPRR) family.
   
  
 0.860
CNFN
Cornifelin.
   
 
 0.759
EVPL
Envoplakin.
      
 0.727
LOC110260465
EF-hand domain-containing protein.
      
 0.557
S100A7
EF-hand domain-containing protein.
      
 0.546
PGLYRP1
20 kDa neutrophil cationic protein.
   
  
 0.518
POGZ
Pogo transposable element with ZNF domain isoform X1.
   
 
 0.512
PSIP1
PC4 and SFRS1 interacting protein 1.
      
 0.485
FCER1A
Fc fragment of IgE receptor Ia.
      
 0.446
KDSR
3-ketodihydrosphingosine reductase; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
      
 0.408
Your Current Organism:
Sus scrofa
NCBI taxonomy Id: 9823
Other names: S. scrofa, pig, pigs, swine, wild boar
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.