TSHB protein (Sus scrofa) - STRING interaction network

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TSHB

Thyrotropin subunit beta; Indispensable for the control of thyroid structure and metabolism. (138 aa)

Predicted Functional Partners:

CGA

0.995

TSHR

0.984

LHCGR

0.958

FSHR

0.957

DRD1

0.925

ADRB2

0.921

NPR1

0.895

ADRB1

0.890

CRHR1

0.889

ADCYAP1R1

0.886

Your Current Organism:

Sus scrofa

NCBI taxonomy Id: 9823
Other names: S. scrofa, pig, pigs, swine, wild boar

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ADCYAP1R1	ADRB1	ENSSSCP00000043415	ENSSSCP00000011344	Pituitary adenylate cyclase-activating polypeptide type I receptor short form; Belongs to the G-protein coupled receptor 2 family.	Beta-1 adrenergic receptor; Beta-adrenergic receptors mediate the catecholamine-induced activation of adenylate cyclase through the action of G proteins. This receptor binds epinephrine and norepinephrine with approximately equal affinity. Mediates Ras activation through G(s)-alpha- and cAMP-mediated signaling (By similarity). Involved in the regulation of sleep/wake behaviors (By similarity).	0.482
ADCYAP1R1	ADRB2	ENSSSCP00000043415	ENSSSCP00000049170	Pituitary adenylate cyclase-activating polypeptide type I receptor short form; Belongs to the G-protein coupled receptor 2 family.	Beta-2 adrenergic receptor; Beta-adrenergic receptors mediate the catecholamine-induced activation of adenylate cyclase through the action of G proteins. The beta-2-adrenergic receptor binds epinephrine with an approximately 30- fold greater affinity than it does norepinephrine (By similarity).	0.482
ADCYAP1R1	CGA	ENSSSCP00000043415	ENSSSCP00000046920	Pituitary adenylate cyclase-activating polypeptide type I receptor short form; Belongs to the G-protein coupled receptor 2 family.	Glycoprotein hormones alpha chain; Shared alpha chain of the active heterodimeric glycoprotein hormones thyrotropin/thyroid stimulating hormone/TSH, lutropin/luteinizing hormone/LH and follitropin/follicle stimulating hormone/FSH. These hormones bind specific receptors on target cells that in turn activate downstream signaling pathways.	0.856
ADCYAP1R1	DRD1	ENSSSCP00000043415	ENSSSCP00000020447	Pituitary adenylate cyclase-activating polypeptide type I receptor short form; Belongs to the G-protein coupled receptor 2 family.	D(1A) dopamine receptor; Dopamine receptor whose activity is mediated by G proteins which activate adenylyl cyclase.	0.481
ADCYAP1R1	FSHR	ENSSSCP00000043415	ENSSSCP00000020856	Pituitary adenylate cyclase-activating polypeptide type I receptor short form; Belongs to the G-protein coupled receptor 2 family.	Follicle-stimulating hormone receptor; G protein-coupled receptor for follitropin, the follicle- stimulating hormone. Through cAMP production activates the downstream PI3K-AKT and ERK1/ERK2 signaling pathways.	0.620
ADCYAP1R1	LHCGR	ENSSSCP00000043415	ENSSSCP00000008988	Pituitary adenylate cyclase-activating polypeptide type I receptor short form; Belongs to the G-protein coupled receptor 2 family.	Lutropin-choriogonadotropic hormone receptor; Receptor for lutropin-choriogonadotropic hormone. The activity of this receptor is mediated by G proteins which activate adenylate cyclase; Belongs to the G-protein coupled receptor 1 family. FSH/LSH/TSH subfamily.	0.465
ADCYAP1R1	TSHB	ENSSSCP00000043415	ENSSSCP00000007199	Pituitary adenylate cyclase-activating polypeptide type I receptor short form; Belongs to the G-protein coupled receptor 2 family.	Thyrotropin subunit beta; Indispensable for the control of thyroid structure and metabolism.	0.886
ADCYAP1R1	TSHR	ENSSSCP00000043415	ENSSSCP00000053542	Pituitary adenylate cyclase-activating polypeptide type I receptor short form; Belongs to the G-protein coupled receptor 2 family.	Thyrotropin receptor; Receptor for the thyroid-stimulating hormone (TSH) or thyrotropin. Also acts as a receptor for the heterodimeric glycoprotein hormone (GPHA2:GPHB5) or thyrostimulin. The activity of this receptor is mediated by G proteins which activate adenylate cyclase. Plays a central role in controlling thyroid cell metabolism.	0.620
ADRB1	ADCYAP1R1	ENSSSCP00000011344	ENSSSCP00000043415	Beta-1 adrenergic receptor; Beta-adrenergic receptors mediate the catecholamine-induced activation of adenylate cyclase through the action of G proteins. This receptor binds epinephrine and norepinephrine with approximately equal affinity. Mediates Ras activation through G(s)-alpha- and cAMP-mediated signaling (By similarity). Involved in the regulation of sleep/wake behaviors (By similarity).	Pituitary adenylate cyclase-activating polypeptide type I receptor short form; Belongs to the G-protein coupled receptor 2 family.	0.482
ADRB1	ADRB2	ENSSSCP00000011344	ENSSSCP00000049170	Beta-1 adrenergic receptor; Beta-adrenergic receptors mediate the catecholamine-induced activation of adenylate cyclase through the action of G proteins. This receptor binds epinephrine and norepinephrine with approximately equal affinity. Mediates Ras activation through G(s)-alpha- and cAMP-mediated signaling (By similarity). Involved in the regulation of sleep/wake behaviors (By similarity).	Beta-2 adrenergic receptor; Beta-adrenergic receptors mediate the catecholamine-induced activation of adenylate cyclase through the action of G proteins. The beta-2-adrenergic receptor binds epinephrine with an approximately 30- fold greater affinity than it does norepinephrine (By similarity).	0.983
ADRB1	CGA	ENSSSCP00000011344	ENSSSCP00000046920	Beta-1 adrenergic receptor; Beta-adrenergic receptors mediate the catecholamine-induced activation of adenylate cyclase through the action of G proteins. This receptor binds epinephrine and norepinephrine with approximately equal affinity. Mediates Ras activation through G(s)-alpha- and cAMP-mediated signaling (By similarity). Involved in the regulation of sleep/wake behaviors (By similarity).	Glycoprotein hormones alpha chain; Shared alpha chain of the active heterodimeric glycoprotein hormones thyrotropin/thyroid stimulating hormone/TSH, lutropin/luteinizing hormone/LH and follitropin/follicle stimulating hormone/FSH. These hormones bind specific receptors on target cells that in turn activate downstream signaling pathways.	0.698
ADRB1	DRD1	ENSSSCP00000011344	ENSSSCP00000020447	Beta-1 adrenergic receptor; Beta-adrenergic receptors mediate the catecholamine-induced activation of adenylate cyclase through the action of G proteins. This receptor binds epinephrine and norepinephrine with approximately equal affinity. Mediates Ras activation through G(s)-alpha- and cAMP-mediated signaling (By similarity). Involved in the regulation of sleep/wake behaviors (By similarity).	D(1A) dopamine receptor; Dopamine receptor whose activity is mediated by G proteins which activate adenylyl cyclase.	0.528
ADRB1	FSHR	ENSSSCP00000011344	ENSSSCP00000020856	Beta-1 adrenergic receptor; Beta-adrenergic receptors mediate the catecholamine-induced activation of adenylate cyclase through the action of G proteins. This receptor binds epinephrine and norepinephrine with approximately equal affinity. Mediates Ras activation through G(s)-alpha- and cAMP-mediated signaling (By similarity). Involved in the regulation of sleep/wake behaviors (By similarity).	Follicle-stimulating hormone receptor; G protein-coupled receptor for follitropin, the follicle- stimulating hormone. Through cAMP production activates the downstream PI3K-AKT and ERK1/ERK2 signaling pathways.	0.717
ADRB1	LHCGR	ENSSSCP00000011344	ENSSSCP00000008988	Beta-1 adrenergic receptor; Beta-adrenergic receptors mediate the catecholamine-induced activation of adenylate cyclase through the action of G proteins. This receptor binds epinephrine and norepinephrine with approximately equal affinity. Mediates Ras activation through G(s)-alpha- and cAMP-mediated signaling (By similarity). Involved in the regulation of sleep/wake behaviors (By similarity).	Lutropin-choriogonadotropic hormone receptor; Receptor for lutropin-choriogonadotropic hormone. The activity of this receptor is mediated by G proteins which activate adenylate cyclase; Belongs to the G-protein coupled receptor 1 family. FSH/LSH/TSH subfamily.	0.528
ADRB1	TSHB	ENSSSCP00000011344	ENSSSCP00000007199	Beta-1 adrenergic receptor; Beta-adrenergic receptors mediate the catecholamine-induced activation of adenylate cyclase through the action of G proteins. This receptor binds epinephrine and norepinephrine with approximately equal affinity. Mediates Ras activation through G(s)-alpha- and cAMP-mediated signaling (By similarity). Involved in the regulation of sleep/wake behaviors (By similarity).	Thyrotropin subunit beta; Indispensable for the control of thyroid structure and metabolism.	0.890
ADRB1	TSHR	ENSSSCP00000011344	ENSSSCP00000053542	Beta-1 adrenergic receptor; Beta-adrenergic receptors mediate the catecholamine-induced activation of adenylate cyclase through the action of G proteins. This receptor binds epinephrine and norepinephrine with approximately equal affinity. Mediates Ras activation through G(s)-alpha- and cAMP-mediated signaling (By similarity). Involved in the regulation of sleep/wake behaviors (By similarity).	Thyrotropin receptor; Receptor for the thyroid-stimulating hormone (TSH) or thyrotropin. Also acts as a receptor for the heterodimeric glycoprotein hormone (GPHA2:GPHB5) or thyrostimulin. The activity of this receptor is mediated by G proteins which activate adenylate cyclase. Plays a central role in controlling thyroid cell metabolism.	0.534
ADRB2	ADCYAP1R1	ENSSSCP00000049170	ENSSSCP00000043415	Beta-2 adrenergic receptor; Beta-adrenergic receptors mediate the catecholamine-induced activation of adenylate cyclase through the action of G proteins. The beta-2-adrenergic receptor binds epinephrine with an approximately 30- fold greater affinity than it does norepinephrine (By similarity).	Pituitary adenylate cyclase-activating polypeptide type I receptor short form; Belongs to the G-protein coupled receptor 2 family.	0.482
ADRB2	ADRB1	ENSSSCP00000049170	ENSSSCP00000011344	Beta-2 adrenergic receptor; Beta-adrenergic receptors mediate the catecholamine-induced activation of adenylate cyclase through the action of G proteins. The beta-2-adrenergic receptor binds epinephrine with an approximately 30- fold greater affinity than it does norepinephrine (By similarity).	Beta-1 adrenergic receptor; Beta-adrenergic receptors mediate the catecholamine-induced activation of adenylate cyclase through the action of G proteins. This receptor binds epinephrine and norepinephrine with approximately equal affinity. Mediates Ras activation through G(s)-alpha- and cAMP-mediated signaling (By similarity). Involved in the regulation of sleep/wake behaviors (By similarity).	0.983
ADRB2	CGA	ENSSSCP00000049170	ENSSSCP00000046920	Beta-2 adrenergic receptor; Beta-adrenergic receptors mediate the catecholamine-induced activation of adenylate cyclase through the action of G proteins. The beta-2-adrenergic receptor binds epinephrine with an approximately 30- fold greater affinity than it does norepinephrine (By similarity).	Glycoprotein hormones alpha chain; Shared alpha chain of the active heterodimeric glycoprotein hormones thyrotropin/thyroid stimulating hormone/TSH, lutropin/luteinizing hormone/LH and follitropin/follicle stimulating hormone/FSH. These hormones bind specific receptors on target cells that in turn activate downstream signaling pathways.	0.698
ADRB2	DRD1	ENSSSCP00000049170	ENSSSCP00000020447	Beta-2 adrenergic receptor; Beta-adrenergic receptors mediate the catecholamine-induced activation of adenylate cyclase through the action of G proteins. The beta-2-adrenergic receptor binds epinephrine with an approximately 30- fold greater affinity than it does norepinephrine (By similarity).	D(1A) dopamine receptor; Dopamine receptor whose activity is mediated by G proteins which activate adenylyl cyclase.	0.528