CD53 protein (Sus scrofa) - STRING interaction network

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Known Interactions

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Predicted Interactions

gene neighborhood

gene fusions

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textmining

co-expression

protein homology

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[Homology]

Score

CD53

Tetraspanin. (219 aa)

Predicted Functional Partners:

LAPTM5

0.834

PTPRC

0.723

CD48

0.713

CD37

0.649

LCP2

0.616

CD82

0.594

TSPAN31

0.573

ITGB2

0.567

CHI3L2

0.555

AIF1

0.547

Your Current Organism:

Sus scrofa

NCBI taxonomy Id: 9823
Other names: S. scrofa, pig, pigs, swine, wild boar

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AIF1	CD53	ENSSSCP00000036374	ENSSSCP00000007253	Allograft inflammatory factor 1; Actin-binding protein that enhances membrane ruffling and RAC activation. Enhances the actin-bundling activity of LCP1. Binds calcium. Plays a role in RAC signaling and in phagocytosis. May play a role in macrophage activation and function. Promotes the proliferation of vascular smooth muscle cells and of T-lymphocytes. Enhances lymphocyte migration. Plays a role in vascular inflammation (By similarity). Has a dual influence on glucose-induced insulin secretion: inhibition at low concentration and stimulation at high concentrations.	Tetraspanin.	0.547
AIF1	ITGB2	ENSSSCP00000036374	ENSSSCP00000044320	Allograft inflammatory factor 1; Actin-binding protein that enhances membrane ruffling and RAC activation. Enhances the actin-bundling activity of LCP1. Binds calcium. Plays a role in RAC signaling and in phagocytosis. May play a role in macrophage activation and function. Promotes the proliferation of vascular smooth muscle cells and of T-lymphocytes. Enhances lymphocyte migration. Plays a role in vascular inflammation (By similarity). Has a dual influence on glucose-induced insulin secretion: inhibition at low concentration and stimulation at high concentrations.	Integrin beta-2; Integrin ITGAL/ITGB2 is a receptor for ICAM1, ICAM2, ICAM3 and ICAM4. Integrin ITGAL/ITGB2 is also a receptor for the secreted form of ubiquitin-like protein ISG15; the interaction is mediated by ITGAL. Integrins ITGAM/ITGB2 and ITGAX/ITGB2 are receptors for the iC3b fragment of the third complement component and for fibrinogen. Integrin ITGAX/ITGB2 recognizes the sequence G-P-R in fibrinogen alpha-chain. Integrin ITGAM/ITGB2 recognizes P1 and P2 peptides of fibrinogen gamma chain. Integrin ITGAM/ITGB2 is also a receptor for factor X. Integrin ITGAD/ITGB2 is a receptor [...]	0.628
CD37	CD53	ENSSSCP00000063306	ENSSSCP00000007253	Tetraspanin.	Tetraspanin.	0.649
CD37	CD82	ENSSSCP00000063306	ENSSSCP00000061151	Tetraspanin.	Tetraspanin.	0.495
CD48	CD53	ENSSSCP00000006800	ENSSSCP00000007253	CD48 antigen isoform X1.	Tetraspanin.	0.713
CD48	ITGB2	ENSSSCP00000006800	ENSSSCP00000044320	CD48 antigen isoform X1.	Integrin beta-2; Integrin ITGAL/ITGB2 is a receptor for ICAM1, ICAM2, ICAM3 and ICAM4. Integrin ITGAL/ITGB2 is also a receptor for the secreted form of ubiquitin-like protein ISG15; the interaction is mediated by ITGAL. Integrins ITGAM/ITGB2 and ITGAX/ITGB2 are receptors for the iC3b fragment of the third complement component and for fibrinogen. Integrin ITGAX/ITGB2 recognizes the sequence G-P-R in fibrinogen alpha-chain. Integrin ITGAM/ITGB2 recognizes P1 and P2 peptides of fibrinogen gamma chain. Integrin ITGAM/ITGB2 is also a receptor for factor X. Integrin ITGAD/ITGB2 is a receptor [...]	0.440
CD48	LCP2	ENSSSCP00000006800	ENSSSCP00000018018	CD48 antigen isoform X1.	Lymphocyte cytosolic protein 2.	0.435
CD48	PTPRC	ENSSSCP00000006800	ENSSSCP00000040401	CD48 antigen isoform X1.	Protein tyrosine phosphatase receptor type C.	0.587
CD53	AIF1	ENSSSCP00000007253	ENSSSCP00000036374	Tetraspanin.	Allograft inflammatory factor 1; Actin-binding protein that enhances membrane ruffling and RAC activation. Enhances the actin-bundling activity of LCP1. Binds calcium. Plays a role in RAC signaling and in phagocytosis. May play a role in macrophage activation and function. Promotes the proliferation of vascular smooth muscle cells and of T-lymphocytes. Enhances lymphocyte migration. Plays a role in vascular inflammation (By similarity). Has a dual influence on glucose-induced insulin secretion: inhibition at low concentration and stimulation at high concentrations.	0.547
CD53	CD37	ENSSSCP00000007253	ENSSSCP00000063306	Tetraspanin.	Tetraspanin.	0.649
CD53	CD48	ENSSSCP00000007253	ENSSSCP00000006800	Tetraspanin.	CD48 antigen isoform X1.	0.713
CD53	CD82	ENSSSCP00000007253	ENSSSCP00000061151	Tetraspanin.	Tetraspanin.	0.594
CD53	CHI3L2	ENSSSCP00000007253	ENSSSCP00000007249	Tetraspanin.	Chitinase 3 like 2; Belongs to the glycosyl hydrolase 18 family.	0.555
CD53	ITGB2	ENSSSCP00000007253	ENSSSCP00000044320	Tetraspanin.	Integrin beta-2; Integrin ITGAL/ITGB2 is a receptor for ICAM1, ICAM2, ICAM3 and ICAM4. Integrin ITGAL/ITGB2 is also a receptor for the secreted form of ubiquitin-like protein ISG15; the interaction is mediated by ITGAL. Integrins ITGAM/ITGB2 and ITGAX/ITGB2 are receptors for the iC3b fragment of the third complement component and for fibrinogen. Integrin ITGAX/ITGB2 recognizes the sequence G-P-R in fibrinogen alpha-chain. Integrin ITGAM/ITGB2 recognizes P1 and P2 peptides of fibrinogen gamma chain. Integrin ITGAM/ITGB2 is also a receptor for factor X. Integrin ITGAD/ITGB2 is a receptor [...]	0.567
CD53	LAPTM5	ENSSSCP00000007253	ENSSSCP00000020632	Tetraspanin.	Lysosomal protein transmembrane 5.	0.834
CD53	LCP2	ENSSSCP00000007253	ENSSSCP00000018018	Tetraspanin.	Lymphocyte cytosolic protein 2.	0.616
CD53	PTPRC	ENSSSCP00000007253	ENSSSCP00000040401	Tetraspanin.	Protein tyrosine phosphatase receptor type C.	0.723
CD53	TSPAN31	ENSSSCP00000007253	ENSSSCP00000052017	Tetraspanin.	Tetraspanin-31.	0.573
CD82	CD37	ENSSSCP00000061151	ENSSSCP00000063306	Tetraspanin.	Tetraspanin.	0.495
CD82	CD53	ENSSSCP00000061151	ENSSSCP00000007253	Tetraspanin.	Tetraspanin.	0.594