BPIFB5 protein (Sus scrofa) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Input:

Neighborhood

Gene fusion

Co-occurrence

Co-expression

Experiments

Databases

Textmining

[Homology]

Score

BPIFB5

Uncharacterized protein. (492 aa)

Predicted Functional Partners:

CLPSL2

0.702

MCFD2

0.700

BPIFA1

0.673

SCGB3A1

0.651

GNG10

0.636

BPIFB1

0.634

ERCC4

0.634

PNPLA1

0.602

OBP

0.599

TCIRG1

0.594

Your Current Organism:

Sus scrofa

NCBI taxonomy Id: 9823
Other names: S. scrofa, pig, pigs, swine, wild boar

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc.

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
BPIFA1	BPIFB1	ENSSSCP00000030681	ENSSSCP00000007732	BPI fold-containing family A member 1; Lipid-binding protein which shows high specificity for the surfactant phospholipid dipalmitoylphosphatidylcholine (DPPC). Plays a role in the innate immune responses of the upper airways. Reduces the surface tension in secretions from airway epithelia and inhibits the formation of biofilm by pathogenic Gram-negative bacteria, such as P.aeruginosa and K.pneumoniae. Negatively regulates proteolytic cleavage of SCNN1G, an event that is required for activation of the epithelial sodium channel (ENaC), and thereby contributes to airway surface liquid ho [...]	Long palate lung and nasal epithelium protein 1.	0.916
BPIFA1	BPIFB5	ENSSSCP00000030681	ENSSSCP00000007733	BPI fold-containing family A member 1; Lipid-binding protein which shows high specificity for the surfactant phospholipid dipalmitoylphosphatidylcholine (DPPC). Plays a role in the innate immune responses of the upper airways. Reduces the surface tension in secretions from airway epithelia and inhibits the formation of biofilm by pathogenic Gram-negative bacteria, such as P.aeruginosa and K.pneumoniae. Negatively regulates proteolytic cleavage of SCNN1G, an event that is required for activation of the epithelial sodium channel (ENaC), and thereby contributes to airway surface liquid ho [...]	Uncharacterized protein.	0.673
BPIFA1	SCGB3A1	ENSSSCP00000030681	ENSSSCP00000014893	BPI fold-containing family A member 1; Lipid-binding protein which shows high specificity for the surfactant phospholipid dipalmitoylphosphatidylcholine (DPPC). Plays a role in the innate immune responses of the upper airways. Reduces the surface tension in secretions from airway epithelia and inhibits the formation of biofilm by pathogenic Gram-negative bacteria, such as P.aeruginosa and K.pneumoniae. Negatively regulates proteolytic cleavage of SCNN1G, an event that is required for activation of the epithelial sodium channel (ENaC), and thereby contributes to airway surface liquid ho [...]	Secretoglobin family 3A member 1.	0.559
BPIFB1	BPIFA1	ENSSSCP00000007732	ENSSSCP00000030681	Long palate lung and nasal epithelium protein 1.	BPI fold-containing family A member 1; Lipid-binding protein which shows high specificity for the surfactant phospholipid dipalmitoylphosphatidylcholine (DPPC). Plays a role in the innate immune responses of the upper airways. Reduces the surface tension in secretions from airway epithelia and inhibits the formation of biofilm by pathogenic Gram-negative bacteria, such as P.aeruginosa and K.pneumoniae. Negatively regulates proteolytic cleavage of SCNN1G, an event that is required for activation of the epithelial sodium channel (ENaC), and thereby contributes to airway surface liquid ho [...]	0.916
BPIFB1	BPIFB5	ENSSSCP00000007732	ENSSSCP00000007733	Long palate lung and nasal epithelium protein 1.	Uncharacterized protein.	0.634
BPIFB1	CLPSL2	ENSSSCP00000007732	ENSSSCP00000001685	Long palate lung and nasal epithelium protein 1.	Uncharacterized protein.	0.620
BPIFB1	ERCC4	ENSSSCP00000007732	ENSSSCP00000008414	Long palate lung and nasal epithelium protein 1.	ERCC excision repair 4, endonuclease catalytic subunit.	0.509
BPIFB1	GNG10	ENSSSCP00000007732	ENSSSCP00000072165	Long palate lung and nasal epithelium protein 1.	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	0.509
BPIFB1	MCFD2	ENSSSCP00000007732	ENSSSCP00000030309	Long palate lung and nasal epithelium protein 1.	Multiple coagulation factor deficiency 2.	0.593
BPIFB1	PNPLA1	ENSSSCP00000007732	ENSSSCP00000001694	Long palate lung and nasal epithelium protein 1.	Patatin like phospholipase domain containing 1.	0.493
BPIFB1	SCGB3A1	ENSSSCP00000007732	ENSSSCP00000014893	Long palate lung and nasal epithelium protein 1.	Secretoglobin family 3A member 1.	0.655
BPIFB1	TCIRG1	ENSSSCP00000007732	ENSSSCP00000013706	Long palate lung and nasal epithelium protein 1.	V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase.	0.473
BPIFB5	BPIFA1	ENSSSCP00000007733	ENSSSCP00000030681	Uncharacterized protein.	BPI fold-containing family A member 1; Lipid-binding protein which shows high specificity for the surfactant phospholipid dipalmitoylphosphatidylcholine (DPPC). Plays a role in the innate immune responses of the upper airways. Reduces the surface tension in secretions from airway epithelia and inhibits the formation of biofilm by pathogenic Gram-negative bacteria, such as P.aeruginosa and K.pneumoniae. Negatively regulates proteolytic cleavage of SCNN1G, an event that is required for activation of the epithelial sodium channel (ENaC), and thereby contributes to airway surface liquid ho [...]	0.673
BPIFB5	BPIFB1	ENSSSCP00000007733	ENSSSCP00000007732	Uncharacterized protein.	Long palate lung and nasal epithelium protein 1.	0.634
BPIFB5	CLPSL2	ENSSSCP00000007733	ENSSSCP00000001685	Uncharacterized protein.	Uncharacterized protein.	0.702
BPIFB5	ERCC4	ENSSSCP00000007733	ENSSSCP00000008414	Uncharacterized protein.	ERCC excision repair 4, endonuclease catalytic subunit.	0.634
BPIFB5	GNG10	ENSSSCP00000007733	ENSSSCP00000072165	Uncharacterized protein.	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	0.636
BPIFB5	MCFD2	ENSSSCP00000007733	ENSSSCP00000030309	Uncharacterized protein.	Multiple coagulation factor deficiency 2.	0.700
BPIFB5	OBP	ENSSSCP00000007733	ENSSSCP00000012876	Uncharacterized protein.	Odorant-binding protein; This protein is found in nasal epithelium and it binds a wide variety of chemical odorants.	0.599
BPIFB5	PNPLA1	ENSSSCP00000007733	ENSSSCP00000001694	Uncharacterized protein.	Patatin like phospholipase domain containing 1.	0.602