STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
VAPBVesicle-associated membrane protein-associated protein B; Participates in the endoplasmic reticulum unfolded protein response (UPR) by inducing ERN1/IRE1 activity. Involved in cellular calcium homeostasis regulation. (309 aa)    
Predicted Functional Partners:
STARD3
StAR related lipid transfer domain containing 3.
    
 0.979
VAPA
VAMP associated protein A.
  
0.973
ATF6
Activating transcription factor 6.
     
 0.935
SNX2
Sorting nexin-2 isoform 1.
   
 
 0.897
C9orf72
C9orf72-SMCR8 complex subunit.
      
 0.870
RMDN3
Regulator of microtubule dynamics 3.
    
 
 0.869
OSBP
Oxysterol-binding protein; Belongs to the OSBP family.
    
 
 0.863
AP1S1
AP complex subunit sigma; Belongs to the adaptor complexes small subunit family.
      
 0.722
BCAP31
B-cell receptor-associated protein 31 isoform b.
   
 0.712
RMDN2
Regulator of microtubule dynamics 2.
    
 
 0.686
Your Current Organism:
Sus scrofa
NCBI taxonomy Id: 9823
Other names: S. scrofa, pig, pigs, swine, wild boar
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.