STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SETD1ASET domain containing 1A, histone lysine methyltransferase. (1703 aa)    
Predicted Functional Partners:
WDR82
WD repeat domain 82.
   
 0.960
RBBP5
RB binding protein 5, histone lysine methyltransferase complex subunit.
    
 0.948
ASH2L
ASH2 like, histone lysine methyltransferase complex subunit.
    
 0.939
CXXC1
CXXC finger protein 1.
   
 0.938
DPY30
Dpy-30 histone methyltransferase complex regulatory subunit.
    
 0.936
WDR5
WD repeat domain 5.
   
 0.853
KMT2B
Lysine methyltransferase 2B.
   
0.824
HCFC2
Host cell factor C2.
   
 0.794
RNF40
E3 ubiquitin protein ligase; Belongs to the BRE1 family.
   
 
 0.755
LOC100621389
Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
    
 0.746
Your Current Organism:
Sus scrofa
NCBI taxonomy Id: 9823
Other names: S. scrofa, pig, pigs, swine, wild boar
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.