STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CAPN15Calpain 15; Belongs to the peptidase C2 family. (1008 aa)    
Predicted Functional Partners:
CAPNS1
Calpain small subunit 1; Regulatory subunit of the calcium-regulated non-lysosomal thiol-protease which catalyzes limited proteolysis of substrates involved in cytoskeletal remodeling and signal transduction.
   
 0.760
CAST
Calpastatin; Specific inhibition of calpain (calcium-dependent cysteine protease). Plays a key role in postmortem tenderization of meat and have been proposed to be involved in muscle protein degradation in living tissue; Belongs to the protease inhibitor I27 (calpastatin) family.
   
 
 0.719
ZSWIM8
Zinc finger SWIM-type containing 8.
      
 0.675
AKAP17A
A-kinase anchoring protein 17A.
      
 0.668
ANKRD49
Ankyrin repeat domain-containing protein 49.
    
 
 0.628
NAGK
N-acetylglucosamine kinase.
      
 0.601
KCTD10
BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 3 isoform 2.
      
 0.554
STX18
Syntaxin 18.
      
 0.554
LIN7B
Protein lin-7 homolog; Plays a role in establishing and maintaining the asymmetric distribution of channels and receptors at the plasma membrane of polarized cells; Belongs to the lin-7 family.
      
 0.548
SLC25A19
Solute carrier family 25 member 19; Belongs to the mitochondrial carrier (TC 2.A.29) family.
      
 0.548
Your Current Organism:
Sus scrofa
NCBI taxonomy Id: 9823
Other names: S. scrofa, pig, pigs, swine, wild boar
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.