GNG13 protein (Sus scrofa) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Current Organism:

Sus scrofa

NCBI taxonomy Id: 9823
Other names: S. scrofa, pig, pigs, swine, wild boar

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structured XML interaction data, according to the 'PSI-MI' data standard

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a flat-file format describing the coordinates and colors of nodes in the network

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... protein annotations:

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
GNAI1	GNAI2	ENSSSCP00000016334	ENSSSCP00000012152	Guanine nucleotide-binding protein G(I) subunit alpha-1 isoform 1.	G protein subunit alpha i2.	0.991
GNAI1	GNAI3	ENSSSCP00000016334	ENSSSCP00000007279	Guanine nucleotide-binding protein G(I) subunit alpha-1 isoform 1.	Guanine nucleotide-binding protein G(K) subunit alpha.	0.991
GNAI1	GNAO1	ENSSSCP00000016334	ENSSSCP00000040441	Guanine nucleotide-binding protein G(I) subunit alpha-1 isoform 1.	Guanine nucleotide-binding protein G(O) subunit alpha isoform b.	0.981
GNAI1	GNAS	ENSSSCP00000016334	ENSSSCP00000029311	Guanine nucleotide-binding protein G(I) subunit alpha-1 isoform 1.	Guanine nucleotide-binding protein G(s) subunit alpha; Guanine nucleotide-binding proteins (G proteins) function as transducers in numerous signaling pathways controlled by G protein- coupled receptors (GPCRs). Signaling involves the activation of adenylyl cyclases, resulting in increased levels of the signaling molecule cAMP. GNAS functions downstream of several GPCRs, including beta-adrenergic receptors. Stimulates the Ras signaling pathway via RAPGEF2.	0.924
GNAI1	GNAT3	ENSSSCP00000016334	ENSSSCP00000016333	Guanine nucleotide-binding protein G(I) subunit alpha-1 isoform 1.	G protein subunit alpha transducin 3.	0.916
GNAI1	GNB3	ENSSSCP00000016334	ENSSSCP00000000727	Guanine nucleotide-binding protein G(I) subunit alpha-1 isoform 1.	Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3 isoform 1.	0.995
GNAI1	GNB4	ENSSSCP00000016334	ENSSSCP00000036910	Guanine nucleotide-binding protein G(I) subunit alpha-1 isoform 1.	G protein subunit beta 4.	0.996
GNAI1	GNB5	ENSSSCP00000016334	ENSSSCP00000031679	Guanine nucleotide-binding protein G(I) subunit alpha-1 isoform 1.	G protein subunit beta 5.	0.995
GNAI1	GNG13	ENSSSCP00000016334	ENSSSCP00000008555	Guanine nucleotide-binding protein G(I) subunit alpha-1 isoform 1.	G protein subunit gamma 13.	0.993
GNAI1	GNG3	ENSSSCP00000016334	ENSSSCP00000032340	Guanine nucleotide-binding protein G(I) subunit alpha-1 isoform 1.	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	0.996
GNAI2	GNAI1	ENSSSCP00000012152	ENSSSCP00000016334	G protein subunit alpha i2.	Guanine nucleotide-binding protein G(I) subunit alpha-1 isoform 1.	0.991
GNAI2	GNAI3	ENSSSCP00000012152	ENSSSCP00000007279	G protein subunit alpha i2.	Guanine nucleotide-binding protein G(K) subunit alpha.	0.991
GNAI2	GNAO1	ENSSSCP00000012152	ENSSSCP00000040441	G protein subunit alpha i2.	Guanine nucleotide-binding protein G(O) subunit alpha isoform b.	0.981
GNAI2	GNAS	ENSSSCP00000012152	ENSSSCP00000029311	G protein subunit alpha i2.	Guanine nucleotide-binding protein G(s) subunit alpha; Guanine nucleotide-binding proteins (G proteins) function as transducers in numerous signaling pathways controlled by G protein- coupled receptors (GPCRs). Signaling involves the activation of adenylyl cyclases, resulting in increased levels of the signaling molecule cAMP. GNAS functions downstream of several GPCRs, including beta-adrenergic receptors. Stimulates the Ras signaling pathway via RAPGEF2.	0.925
GNAI2	GNAT3	ENSSSCP00000012152	ENSSSCP00000016333	G protein subunit alpha i2.	G protein subunit alpha transducin 3.	0.916
GNAI2	GNB3	ENSSSCP00000012152	ENSSSCP00000000727	G protein subunit alpha i2.	Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3 isoform 1.	0.997
GNAI2	GNB4	ENSSSCP00000012152	ENSSSCP00000036910	G protein subunit alpha i2.	G protein subunit beta 4.	0.995
GNAI2	GNB5	ENSSSCP00000012152	ENSSSCP00000031679	G protein subunit alpha i2.	G protein subunit beta 5.	0.991
GNAI2	GNG13	ENSSSCP00000012152	ENSSSCP00000008555	G protein subunit alpha i2.	G protein subunit gamma 13.	0.992
GNAI2	GNG3	ENSSSCP00000012152	ENSSSCP00000032340	G protein subunit alpha i2.	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	0.990