node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
G6PC | G6PC3 | ENSSSCP00000046238 | ENSSSCP00000055002 | Glucose-6-phosphatase; Belongs to the glucose-6-phosphatase family. | Glucose-6-phosphatase; Belongs to the glucose-6-phosphatase family. | 0.908 |
G6PC | GPI | ENSSSCP00000046238 | ENSSSCP00000003094 | Glucose-6-phosphatase; Belongs to the glucose-6-phosphatase family. | Glucose-6-phosphate isomerase; In the cytoplasm, catalyzes the conversion of glucose-6- phosphate to fructose-6-phosphate, the second step in glycolysis, and the reverse reaction during gluconeogenesis (By similarity). Besides it's role as a glycolytic enzyme, also acts as a secreted cytokine: acts as an angiogenic factor (AMF) that stimulates endothelial cell motility. Acts as a neurotrophic factor, neuroleukin, for spinal and sensory neurons. It is secreted by lectin-stimulated T-cells and induces immunoglobulin secretion (By similarity). | 0.925 |
G6PC | HK1 | ENSSSCP00000046238 | ENSSSCP00000070834 | Glucose-6-phosphatase; Belongs to the glucose-6-phosphatase family. | Uncharacterized protein. | 0.955 |
G6PC | HK2 | ENSSSCP00000046238 | ENSSSCP00000008819 | Glucose-6-phosphatase; Belongs to the glucose-6-phosphatase family. | Hexokinase-2; Catalyzes the phosphorylation of hexose, such as D-glucose and D-fructose, to hexose 6-phosphate (D-glucose 6-phosphate and D- fructose 6-phosphate, respectively). Mediates the initial step of glycolysis by catalyzing phosphorylation of D-glucose to D-glucose 6- phosphate. Plays a key role in maintaining the integrity of the outer mitochondrial membrane by preventing the release of apoptogenic molecules from the intermembrane space and subsequent apoptosis. Belongs to the hexokinase family. | 0.955 |
G6PC | PFKL | ENSSSCP00000046238 | ENSSSCP00000042883 | Glucose-6-phosphatase; Belongs to the glucose-6-phosphatase family. | 6-phosphofructokinase; Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Eukaryotic two domain clade "E" sub-subfamily. | 0.463 |
G6PC | PFKM | ENSSSCP00000046238 | ENSSSCP00000031307 | Glucose-6-phosphatase; Belongs to the glucose-6-phosphatase family. | ATP-dependent 6-phosphofructokinase, muscle type; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Eukaryotic two domain clade 'E' sub-subfamily. | 0.516 |
G6PC3 | G6PC | ENSSSCP00000055002 | ENSSSCP00000046238 | Glucose-6-phosphatase; Belongs to the glucose-6-phosphatase family. | Glucose-6-phosphatase; Belongs to the glucose-6-phosphatase family. | 0.908 |
G6PC3 | GPI | ENSSSCP00000055002 | ENSSSCP00000003094 | Glucose-6-phosphatase; Belongs to the glucose-6-phosphatase family. | Glucose-6-phosphate isomerase; In the cytoplasm, catalyzes the conversion of glucose-6- phosphate to fructose-6-phosphate, the second step in glycolysis, and the reverse reaction during gluconeogenesis (By similarity). Besides it's role as a glycolytic enzyme, also acts as a secreted cytokine: acts as an angiogenic factor (AMF) that stimulates endothelial cell motility. Acts as a neurotrophic factor, neuroleukin, for spinal and sensory neurons. It is secreted by lectin-stimulated T-cells and induces immunoglobulin secretion (By similarity). | 0.926 |
G6PC3 | HK1 | ENSSSCP00000055002 | ENSSSCP00000070834 | Glucose-6-phosphatase; Belongs to the glucose-6-phosphatase family. | Uncharacterized protein. | 0.955 |
G6PC3 | HK2 | ENSSSCP00000055002 | ENSSSCP00000008819 | Glucose-6-phosphatase; Belongs to the glucose-6-phosphatase family. | Hexokinase-2; Catalyzes the phosphorylation of hexose, such as D-glucose and D-fructose, to hexose 6-phosphate (D-glucose 6-phosphate and D- fructose 6-phosphate, respectively). Mediates the initial step of glycolysis by catalyzing phosphorylation of D-glucose to D-glucose 6- phosphate. Plays a key role in maintaining the integrity of the outer mitochondrial membrane by preventing the release of apoptogenic molecules from the intermembrane space and subsequent apoptosis. Belongs to the hexokinase family. | 0.954 |
G6PC3 | PFKL | ENSSSCP00000055002 | ENSSSCP00000042883 | Glucose-6-phosphatase; Belongs to the glucose-6-phosphatase family. | 6-phosphofructokinase; Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Eukaryotic two domain clade "E" sub-subfamily. | 0.465 |
G6PC3 | PFKM | ENSSSCP00000055002 | ENSSSCP00000031307 | Glucose-6-phosphatase; Belongs to the glucose-6-phosphatase family. | ATP-dependent 6-phosphofructokinase, muscle type; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Eukaryotic two domain clade 'E' sub-subfamily. | 0.517 |
GPI | G6PC | ENSSSCP00000003094 | ENSSSCP00000046238 | Glucose-6-phosphate isomerase; In the cytoplasm, catalyzes the conversion of glucose-6- phosphate to fructose-6-phosphate, the second step in glycolysis, and the reverse reaction during gluconeogenesis (By similarity). Besides it's role as a glycolytic enzyme, also acts as a secreted cytokine: acts as an angiogenic factor (AMF) that stimulates endothelial cell motility. Acts as a neurotrophic factor, neuroleukin, for spinal and sensory neurons. It is secreted by lectin-stimulated T-cells and induces immunoglobulin secretion (By similarity). | Glucose-6-phosphatase; Belongs to the glucose-6-phosphatase family. | 0.925 |
GPI | G6PC3 | ENSSSCP00000003094 | ENSSSCP00000055002 | Glucose-6-phosphate isomerase; In the cytoplasm, catalyzes the conversion of glucose-6- phosphate to fructose-6-phosphate, the second step in glycolysis, and the reverse reaction during gluconeogenesis (By similarity). Besides it's role as a glycolytic enzyme, also acts as a secreted cytokine: acts as an angiogenic factor (AMF) that stimulates endothelial cell motility. Acts as a neurotrophic factor, neuroleukin, for spinal and sensory neurons. It is secreted by lectin-stimulated T-cells and induces immunoglobulin secretion (By similarity). | Glucose-6-phosphatase; Belongs to the glucose-6-phosphatase family. | 0.926 |
GPI | HK1 | ENSSSCP00000003094 | ENSSSCP00000070834 | Glucose-6-phosphate isomerase; In the cytoplasm, catalyzes the conversion of glucose-6- phosphate to fructose-6-phosphate, the second step in glycolysis, and the reverse reaction during gluconeogenesis (By similarity). Besides it's role as a glycolytic enzyme, also acts as a secreted cytokine: acts as an angiogenic factor (AMF) that stimulates endothelial cell motility. Acts as a neurotrophic factor, neuroleukin, for spinal and sensory neurons. It is secreted by lectin-stimulated T-cells and induces immunoglobulin secretion (By similarity). | Uncharacterized protein. | 0.989 |
GPI | HK2 | ENSSSCP00000003094 | ENSSSCP00000008819 | Glucose-6-phosphate isomerase; In the cytoplasm, catalyzes the conversion of glucose-6- phosphate to fructose-6-phosphate, the second step in glycolysis, and the reverse reaction during gluconeogenesis (By similarity). Besides it's role as a glycolytic enzyme, also acts as a secreted cytokine: acts as an angiogenic factor (AMF) that stimulates endothelial cell motility. Acts as a neurotrophic factor, neuroleukin, for spinal and sensory neurons. It is secreted by lectin-stimulated T-cells and induces immunoglobulin secretion (By similarity). | Hexokinase-2; Catalyzes the phosphorylation of hexose, such as D-glucose and D-fructose, to hexose 6-phosphate (D-glucose 6-phosphate and D- fructose 6-phosphate, respectively). Mediates the initial step of glycolysis by catalyzing phosphorylation of D-glucose to D-glucose 6- phosphate. Plays a key role in maintaining the integrity of the outer mitochondrial membrane by preventing the release of apoptogenic molecules from the intermembrane space and subsequent apoptosis. Belongs to the hexokinase family. | 0.986 |
GPI | PFKFB1 | ENSSSCP00000003094 | ENSSSCP00000070040 | Glucose-6-phosphate isomerase; In the cytoplasm, catalyzes the conversion of glucose-6- phosphate to fructose-6-phosphate, the second step in glycolysis, and the reverse reaction during gluconeogenesis (By similarity). Besides it's role as a glycolytic enzyme, also acts as a secreted cytokine: acts as an angiogenic factor (AMF) that stimulates endothelial cell motility. Acts as a neurotrophic factor, neuroleukin, for spinal and sensory neurons. It is secreted by lectin-stimulated T-cells and induces immunoglobulin secretion (By similarity). | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1. | 0.609 |
GPI | PFKFB2 | ENSSSCP00000003094 | ENSSSCP00000016603 | Glucose-6-phosphate isomerase; In the cytoplasm, catalyzes the conversion of glucose-6- phosphate to fructose-6-phosphate, the second step in glycolysis, and the reverse reaction during gluconeogenesis (By similarity). Besides it's role as a glycolytic enzyme, also acts as a secreted cytokine: acts as an angiogenic factor (AMF) that stimulates endothelial cell motility. Acts as a neurotrophic factor, neuroleukin, for spinal and sensory neurons. It is secreted by lectin-stimulated T-cells and induces immunoglobulin secretion (By similarity). | 6-phosphofructo-2-kinase/fructose-2, 6-bisphosphatase 2 isoform X1. | 0.609 |
GPI | PFKFB3 | ENSSSCP00000003094 | ENSSSCP00000011873 | Glucose-6-phosphate isomerase; In the cytoplasm, catalyzes the conversion of glucose-6- phosphate to fructose-6-phosphate, the second step in glycolysis, and the reverse reaction during gluconeogenesis (By similarity). Besides it's role as a glycolytic enzyme, also acts as a secreted cytokine: acts as an angiogenic factor (AMF) that stimulates endothelial cell motility. Acts as a neurotrophic factor, neuroleukin, for spinal and sensory neurons. It is secreted by lectin-stimulated T-cells and induces immunoglobulin secretion (By similarity). | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3. | 0.609 |
GPI | PFKL | ENSSSCP00000003094 | ENSSSCP00000042883 | Glucose-6-phosphate isomerase; In the cytoplasm, catalyzes the conversion of glucose-6- phosphate to fructose-6-phosphate, the second step in glycolysis, and the reverse reaction during gluconeogenesis (By similarity). Besides it's role as a glycolytic enzyme, also acts as a secreted cytokine: acts as an angiogenic factor (AMF) that stimulates endothelial cell motility. Acts as a neurotrophic factor, neuroleukin, for spinal and sensory neurons. It is secreted by lectin-stimulated T-cells and induces immunoglobulin secretion (By similarity). | 6-phosphofructokinase; Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Eukaryotic two domain clade "E" sub-subfamily. | 0.991 |