• Version:
  • 11.0 (preview - - version 10.5 still available here)
STRINGSTRING
PRKCE protein (Sus scrofa) - STRING interaction network
"PRKCE" - Protein kinase C epsilon type in Sus scrofa
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PRKCEProtein kinase C epsilon type; Calcium-independent, phospholipid- and diacylglycerol (DAG)-dependent serine/threonine-protein kinase that plays essential roles in the regulation of multiple cellular processes linked to cytoskeletal proteins, such as cell adhesion, motility, migration and cell cycle, functions in neuron growth and ion channel regulation, and is involved in immune response, cancer cell invasion and regulation of apoptosis. Mediates cell adhesion to the extracellular matrix via integrin-dependent signaling, by mediating angiotensin-2-induced activation of integrin beta-1 [...] (600 aa)    
Predicted Functional Partners:
YWHAZ
Uncharacterized protein; Belongs to the 14-3-3 family (248 aa)
       
      0.954
SHC1
SHC adaptor protein 1; SHC (Src homology 2 domain containing) transforming protein 1 (584 aa)
       
  0.907
PRKCD
Protein kinase C delta type; Calcium-independent, phospholipid- and diacylglycerol (DAG)-dependent serine/threonine-protein kinase that plays contrasting roles in cell death and cell survival by functioning as a pro-apoptotic protein during DNA damage-induced apoptosis, but acting as an anti-apoptotic protein during cytokine receptor- initiated cell death, is involved in tumor suppression (675 aa)
         
0.904
MARCKS
Myristoylated alanine-rich protein kinase C substrate (181 aa)
       
  0.896
BRAF
B-Raf proto-oncogene, serine/threonine kinase (754 aa)
     
0.894
TRPV1
Transient receptor potential cation channel subfamily V member 1; Belongs to the transient receptor (TC 1.A.4) family (827 aa)
         
  0.870
KRAS
KRAS proto-oncogene, GTPase; Kirsten rat sarcoma viral oncogene homolog (216 aa)
     
  0.859
NRAS
GTPase NRas; Ras proteins bind GDP/GTP and possess intrinsic GTPase activity; Belongs to the small GTPase superfamily. Ras family (189 aa)
     
  0.859
LOC733611
Sus scrofa protein phosphatase 1 catalytic subunit alpha isoform (LOC733611), mRNA (330 aa)
     
  0.855
PPP1CC
Protein phosphatase 1, catalytic subunit, gamma isozyme (321 aa)
     
  0.855
Your Current Organism:
Sus scrofa
NCBI taxonomy Id: 9823
Other names: S. scrofa, Sus scrofa, pig, pigs, swine, wild boar
Server load: low (7%) [HD]