STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
OTOP1Otopetrin 1. (612 aa)    
Predicted Functional Partners:
OC90
Uncharacterized protein.
      
 0.922
DRD1
D(1A) dopamine receptor; Dopamine receptor whose activity is mediated by G proteins which activate adenylyl cyclase.
 
    
 0.884
DRD2
Dopamine receptor D2; Belongs to the G-protein coupled receptor 1 family.
 
    
 0.871
DRD5
Dopamine receptor D5; Belongs to the G-protein coupled receptor 1 family.
 
    
 0.839
NGB
Neuroglobin; Involved in oxygen transport in the brain. Hexacoordinate globin, displaying competitive binding of oxygen or the distal His residue to the iron atom. Not capable of penetrating cell membranes (By similarity).
      
 0.728
CALHM1
Calcium homeostasis modulator 1.
   
  
 0.673
SLC30A4
Solute carrier family 30 member 4.
   
  
 0.658
PLCB2
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes.
      
 0.650
PKD2L1
Polycystin 2 like 1, transient receptor potential cation channel.
      
 0.647
CALHM3
Calcium homeostasis modulator 3.
   
  
 0.605
Your Current Organism:
Sus scrofa
NCBI taxonomy Id: 9823
Other names: S. scrofa, pig, pigs, swine, wild boar
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.