SLIT2 protein (Sus scrofa) - STRING interaction network

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Known Interactions

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Predicted Interactions

gene neighborhood

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textmining

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protein homology

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[Homology]

Score

SLIT2

Slit guidance ligand 2. (1542 aa)

Predicted Functional Partners:

ROBO1

0.996

ROBO2

0.942

ROBO4

0.931

GPC1

0.845

ROBO3

0.739

ADGRL3

0.685

ADGRL2

0.658

SEMA3A

0.655

NTN1

0.653

ADGRL1

0.645

Your Current Organism:

Sus scrofa

NCBI taxonomy Id: 9823
Other names: S. scrofa, pig, pigs, swine, wild boar

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ADGRL1	SLIT2	ENSSSCP00000037086	ENSSSCP00000009325	Adhesion G protein-coupled receptor L1; Belongs to the G-protein coupled receptor 2 family.	Slit guidance ligand 2.	0.645
ADGRL2	SLIT2	ENSSSCP00000052051	ENSSSCP00000009325	Adhesion G protein-coupled receptor L2; Belongs to the G-protein coupled receptor 2 family.	Slit guidance ligand 2.	0.658
ADGRL3	ROBO1	ENSSSCP00000035950	ENSSSCP00000067400	Adhesion G protein-coupled receptor L3; Belongs to the G-protein coupled receptor 2 family.	Roundabout guidance receptor 1.	0.579
ADGRL3	SLIT2	ENSSSCP00000035950	ENSSSCP00000009325	Adhesion G protein-coupled receptor L3; Belongs to the G-protein coupled receptor 2 family.	Slit guidance ligand 2.	0.685
GPC1	SLIT2	ENSSSCP00000047245	ENSSSCP00000009325	Glypican 1; Cell surface proteoglycan that bears heparan sulfate. Belongs to the glypican family.	Slit guidance ligand 2.	0.845
NTN1	ROBO1	ENSSSCP00000066172	ENSSSCP00000067400	Netrin-1; Netrins control guidance of CNS commissural axons and peripheral motor axons. Its association with either DCC or some UNC5 receptors will lead to axon attraction or repulsion, respectively. Binding to UNC5C might cause dissociation of UNC5C from polymerized TUBB3 in microtubules and thereby lead to increased microtubule dynamics and axon repulsion (By similarity). Involved in dorsal root ganglion axon projection towards the spinal cord (By similarity). It also serves as a survival factor via its association with its receptors which prevent the initiation of apoptosis. Involve [...]	Roundabout guidance receptor 1.	0.531
NTN1	ROBO2	ENSSSCP00000066172	ENSSSCP00000022197	Netrin-1; Netrins control guidance of CNS commissural axons and peripheral motor axons. Its association with either DCC or some UNC5 receptors will lead to axon attraction or repulsion, respectively. Binding to UNC5C might cause dissociation of UNC5C from polymerized TUBB3 in microtubules and thereby lead to increased microtubule dynamics and axon repulsion (By similarity). Involved in dorsal root ganglion axon projection towards the spinal cord (By similarity). It also serves as a survival factor via its association with its receptors which prevent the initiation of apoptosis. Involve [...]	Roundabout homolog 2 isoform X5.	0.579
NTN1	ROBO3	ENSSSCP00000066172	ENSSSCP00000016124	Netrin-1; Netrins control guidance of CNS commissural axons and peripheral motor axons. Its association with either DCC or some UNC5 receptors will lead to axon attraction or repulsion, respectively. Binding to UNC5C might cause dissociation of UNC5C from polymerized TUBB3 in microtubules and thereby lead to increased microtubule dynamics and axon repulsion (By similarity). Involved in dorsal root ganglion axon projection towards the spinal cord (By similarity). It also serves as a survival factor via its association with its receptors which prevent the initiation of apoptosis. Involve [...]	Roundabout guidance receptor 3.	0.427
NTN1	SEMA3A	ENSSSCP00000066172	ENSSSCP00000026074	Netrin-1; Netrins control guidance of CNS commissural axons and peripheral motor axons. Its association with either DCC or some UNC5 receptors will lead to axon attraction or repulsion, respectively. Binding to UNC5C might cause dissociation of UNC5C from polymerized TUBB3 in microtubules and thereby lead to increased microtubule dynamics and axon repulsion (By similarity). Involved in dorsal root ganglion axon projection towards the spinal cord (By similarity). It also serves as a survival factor via its association with its receptors which prevent the initiation of apoptosis. Involve [...]	Semaphorin 3A; Belongs to the semaphorin family.	0.759
NTN1	SLIT2	ENSSSCP00000066172	ENSSSCP00000009325	Netrin-1; Netrins control guidance of CNS commissural axons and peripheral motor axons. Its association with either DCC or some UNC5 receptors will lead to axon attraction or repulsion, respectively. Binding to UNC5C might cause dissociation of UNC5C from polymerized TUBB3 in microtubules and thereby lead to increased microtubule dynamics and axon repulsion (By similarity). Involved in dorsal root ganglion axon projection towards the spinal cord (By similarity). It also serves as a survival factor via its association with its receptors which prevent the initiation of apoptosis. Involve [...]	Slit guidance ligand 2.	0.653
ROBO1	ADGRL3	ENSSSCP00000067400	ENSSSCP00000035950	Roundabout guidance receptor 1.	Adhesion G protein-coupled receptor L3; Belongs to the G-protein coupled receptor 2 family.	0.579
ROBO1	NTN1	ENSSSCP00000067400	ENSSSCP00000066172	Roundabout guidance receptor 1.	Netrin-1; Netrins control guidance of CNS commissural axons and peripheral motor axons. Its association with either DCC or some UNC5 receptors will lead to axon attraction or repulsion, respectively. Binding to UNC5C might cause dissociation of UNC5C from polymerized TUBB3 in microtubules and thereby lead to increased microtubule dynamics and axon repulsion (By similarity). Involved in dorsal root ganglion axon projection towards the spinal cord (By similarity). It also serves as a survival factor via its association with its receptors which prevent the initiation of apoptosis. Involve [...]	0.531
ROBO1	ROBO3	ENSSSCP00000067400	ENSSSCP00000016124	Roundabout guidance receptor 1.	Roundabout guidance receptor 3.	0.917
ROBO1	ROBO4	ENSSSCP00000067400	ENSSSCP00000016125	Roundabout guidance receptor 1.	Roundabout guidance receptor 4.	0.418
ROBO1	SEMA3A	ENSSSCP00000067400	ENSSSCP00000026074	Roundabout guidance receptor 1.	Semaphorin 3A; Belongs to the semaphorin family.	0.419
ROBO1	SLIT2	ENSSSCP00000067400	ENSSSCP00000009325	Roundabout guidance receptor 1.	Slit guidance ligand 2.	0.996
ROBO2	NTN1	ENSSSCP00000022197	ENSSSCP00000066172	Roundabout homolog 2 isoform X5.	Netrin-1; Netrins control guidance of CNS commissural axons and peripheral motor axons. Its association with either DCC or some UNC5 receptors will lead to axon attraction or repulsion, respectively. Binding to UNC5C might cause dissociation of UNC5C from polymerized TUBB3 in microtubules and thereby lead to increased microtubule dynamics and axon repulsion (By similarity). Involved in dorsal root ganglion axon projection towards the spinal cord (By similarity). It also serves as a survival factor via its association with its receptors which prevent the initiation of apoptosis. Involve [...]	0.579
ROBO2	ROBO4	ENSSSCP00000022197	ENSSSCP00000016125	Roundabout homolog 2 isoform X5.	Roundabout guidance receptor 4.	0.529
ROBO2	SEMA3A	ENSSSCP00000022197	ENSSSCP00000026074	Roundabout homolog 2 isoform X5.	Semaphorin 3A; Belongs to the semaphorin family.	0.463
ROBO2	SLIT2	ENSSSCP00000022197	ENSSSCP00000009325	Roundabout homolog 2 isoform X5.	Slit guidance ligand 2.	0.942