STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ETFDHElectron transfer flavoprotein-ubiquinone oxidoreductase, mitochondrial; Accepts electrons from ETF and reduces ubiquinone. (615 aa)    
Predicted Functional Partners:
ETFB
Electron transfer flavoprotein subunit beta; Heterodimeric electron transfer flavoprotein that accepts electrons from several mitochondrial dehydrogenases, including acyl-CoA dehydrogenases, glutaryl-CoA and sarcosine dehydrogenase. It transfers the electrons to the main mitochondrial respiratory chain via ETF- ubiquinone oxidoreductase. Required for normal mitochondrial fatty acid oxidation and normal amino acid metabolism. ETFB binds an AMP molecule that probably has a purely structural role.
 
 0.998
ETFA
Electron transfer flavoprotein subunit alpha.
 
 0.998
HADHB
Uncharacterized protein; Belongs to the thiolase-like superfamily. Thiolase family.
  
 
 0.895
HSDL2
Hydroxysteroid dehydrogenase like 2.
  
 
 0.810
ACAA2
Uncharacterized protein; Belongs to the thiolase-like superfamily. Thiolase family.
  
 
 0.776
COQ2
4-hydroxybenzoate polyprenyltransferase, mitochondrial; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of coenzyme Q (CoQ) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate.
   
  
 0.741
CHCHD3
MICOS complex subunit; Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane.
   
  
 0.738
LOC110256626
Proline dehydrogenase; Converts proline to delta-1-pyrroline-5-carboxylate.
      
 0.731
NDUFS2
NADH dehydrogenase ubiquinone iron-sulfur protein 2, mitochondrial isoform 1; Belongs to the complex I 49 kDa subunit family.
   
  
 0.725
UQCRFS1
Ubiquinol-cytochrome c reductase, Rieske iron-sulfur polypeptide 1.
   
 
 0.696
Your Current Organism:
Sus scrofa
NCBI taxonomy Id: 9823
Other names: S. scrofa, pig, pigs, swine, wild boar
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