AFP protein (Sus scrofa) - STRING interaction network

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AFP

Alpha-fetoprotein; Binds copper, nickel, and fatty acids as well as, and bilirubin less well than, serum albumin; Belongs to the ALB/AFP/VDB family. (610 aa)

Predicted Functional Partners:

LOC102166306

0.873

SERPINA1

0.848

NANOG

0.841

HNF4A

0.807

SOX17

0.805

AHSG

0.805

F2

0.732

FOXA2

0.724

ORM1

0.720

PLG

0.717

Your Current Organism:

Sus scrofa

NCBI taxonomy Id: 9823
Other names: S. scrofa, pig, pigs, swine, wild boar

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AFP	AHSG	ENSSSCP00000009550	ENSSSCP00000054117	Alpha-fetoprotein; Binds copper, nickel, and fatty acids as well as, and bilirubin less well than, serum albumin; Belongs to the ALB/AFP/VDB family.	Alpha-2-HS-glycoprotein.	0.805
AFP	F2	ENSSSCP00000009550	ENSSSCP00000014081	Alpha-fetoprotein; Binds copper, nickel, and fatty acids as well as, and bilirubin less well than, serum albumin; Belongs to the ALB/AFP/VDB family.	Activation peptide fragment 1; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing (By similarity).	0.732
AFP	FOXA2	ENSSSCP00000009550	ENSSSCP00000035009	Alpha-fetoprotein; Binds copper, nickel, and fatty acids as well as, and bilirubin less well than, serum albumin; Belongs to the ALB/AFP/VDB family.	Hepatocyte nuclear factor 3-beta isoform 1.	0.724
AFP	HNF4A	ENSSSCP00000009550	ENSSSCP00000067518	Alpha-fetoprotein; Binds copper, nickel, and fatty acids as well as, and bilirubin less well than, serum albumin; Belongs to the ALB/AFP/VDB family.	Hepatocyte nuclear factor 4 alpha.	0.807
AFP	LOC102166306	ENSSSCP00000009550	ENSSSCP00000058301	Alpha-fetoprotein; Binds copper, nickel, and fatty acids as well as, and bilirubin less well than, serum albumin; Belongs to the ALB/AFP/VDB family.	Alpha-fetoprotein isoform 1.	0.873
AFP	NANOG	ENSSSCP00000009550	ENSSSCP00000056364	Alpha-fetoprotein; Binds copper, nickel, and fatty acids as well as, and bilirubin less well than, serum albumin; Belongs to the ALB/AFP/VDB family.	Homeobox domain-containing protein.	0.841
AFP	ORM1	ENSSSCP00000009550	ENSSSCP00000070617	Alpha-fetoprotein; Binds copper, nickel, and fatty acids as well as, and bilirubin less well than, serum albumin; Belongs to the ALB/AFP/VDB family.	Lipocln_cytosolic_FA-bd_dom domain-containing protein.	0.720
AFP	PLG	ENSSSCP00000009550	ENSSSCP00000069662	Alpha-fetoprotein; Binds copper, nickel, and fatty acids as well as, and bilirubin less well than, serum albumin; Belongs to the ALB/AFP/VDB family.	Plasmin heavy chain A, short form; Plasmin dissolves the fibrin of blood clots and acts as a proteolytic factor in a variety of other processes including embryonic development, tissue remodeling, tumor invasion, and inflammation. In ovulation, weakens the walls of the Graafian follicle. It activates the urokinase-type plasminogen activator, collagenases and several complement zymogens, such as C1 and C5. Cleavage of fibronectin and laminin leads to cell detachment and apoptosis. Also cleaves fibrin, thrombospondin and von Willebrand factor. Its role in tissue remodeling and tumor invas [...]	0.717
AFP	SERPINA1	ENSSSCP00000009550	ENSSSCP00000002681	Alpha-fetoprotein; Binds copper, nickel, and fatty acids as well as, and bilirubin less well than, serum albumin; Belongs to the ALB/AFP/VDB family.	Alpha-1-antitrypsin; Inhibitor of serine proteases. Its primary target is elastase, but it also has a moderate affinity for plasmin and thrombin (By similarity).	0.848
AFP	SOX17	ENSSSCP00000009550	ENSSSCP00000006669	Alpha-fetoprotein; Binds copper, nickel, and fatty acids as well as, and bilirubin less well than, serum albumin; Belongs to the ALB/AFP/VDB family.	SRY-box transcription factor 17.	0.805
AHSG	AFP	ENSSSCP00000054117	ENSSSCP00000009550	Alpha-2-HS-glycoprotein.	Alpha-fetoprotein; Binds copper, nickel, and fatty acids as well as, and bilirubin less well than, serum albumin; Belongs to the ALB/AFP/VDB family.	0.805
AHSG	F2	ENSSSCP00000054117	ENSSSCP00000014081	Alpha-2-HS-glycoprotein.	Activation peptide fragment 1; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing (By similarity).	0.978
AHSG	LOC102166306	ENSSSCP00000054117	ENSSSCP00000058301	Alpha-2-HS-glycoprotein.	Alpha-fetoprotein isoform 1.	0.720
AHSG	ORM1	ENSSSCP00000054117	ENSSSCP00000070617	Alpha-2-HS-glycoprotein.	Lipocln_cytosolic_FA-bd_dom domain-containing protein.	0.722
AHSG	PLG	ENSSSCP00000054117	ENSSSCP00000069662	Alpha-2-HS-glycoprotein.	Plasmin heavy chain A, short form; Plasmin dissolves the fibrin of blood clots and acts as a proteolytic factor in a variety of other processes including embryonic development, tissue remodeling, tumor invasion, and inflammation. In ovulation, weakens the walls of the Graafian follicle. It activates the urokinase-type plasminogen activator, collagenases and several complement zymogens, such as C1 and C5. Cleavage of fibronectin and laminin leads to cell detachment and apoptosis. Also cleaves fibrin, thrombospondin and von Willebrand factor. Its role in tissue remodeling and tumor invas [...]	0.932
AHSG	SERPINA1	ENSSSCP00000054117	ENSSSCP00000002681	Alpha-2-HS-glycoprotein.	Alpha-1-antitrypsin; Inhibitor of serine proteases. Its primary target is elastase, but it also has a moderate affinity for plasmin and thrombin (By similarity).	0.838
F2	AFP	ENSSSCP00000014081	ENSSSCP00000009550	Activation peptide fragment 1; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing (By similarity).	Alpha-fetoprotein; Binds copper, nickel, and fatty acids as well as, and bilirubin less well than, serum albumin; Belongs to the ALB/AFP/VDB family.	0.732
F2	AHSG	ENSSSCP00000014081	ENSSSCP00000054117	Activation peptide fragment 1; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing (By similarity).	Alpha-2-HS-glycoprotein.	0.978
F2	LOC102166306	ENSSSCP00000014081	ENSSSCP00000058301	Activation peptide fragment 1; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing (By similarity).	Alpha-fetoprotein isoform 1.	0.547
F2	ORM1	ENSSSCP00000014081	ENSSSCP00000070617	Activation peptide fragment 1; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing (By similarity).	Lipocln_cytosolic_FA-bd_dom domain-containing protein.	0.445