STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CAMK2DCalcium/calmodulin-dependent protein kinase type II subunit delta; Calcium/calmodulin-dependent protein kinase involved in the regulation of Ca(2+) homeostatis and excitation-contraction coupling (ECC) in heart by targeting ion channels, transporters and accessory proteins involved in Ca(2+) influx into the myocyte, Ca(2+) release from the sarcoplasmic reticulum (SR), SR Ca(2+) uptake and Na(+) and K(+) channel transport. Targets also transcription factors and signaling molecules to regulate heart function. In its activated form, is involved in the pathogenesis of dilated cardiomyopath [...] (532 aa)    
Predicted Functional Partners:
MPP1
55 kDa erythrocyte membrane protein isoform 1; Belongs to the MAGUK family.
 
 
 
 0.879
GRIN2B
Glutamate ionotropic receptor NMDA type subunit 2B.
   
 0.785
MPP2
Membrane palmitoylated protein 2; Belongs to the MAGUK family.
 
 
 
 0.779
MPP6
MAGUK p55 subfamily member 6 isoform X1; Belongs to the MAGUK family.
 
 
 
 0.741
PPP3CA
Serine/threonine-protein phosphatase.
   
 
 0.732
GRIA1
Glutamate ionotropic receptor AMPA type subunit 1.
   
 0.721
LRRC7
Leucine rich repeat containing 7.
   
 0.719
GRIN2A
Glutamate ionotropic receptor NMDA type subunit 2A.
   
 0.701
ACTN2
Uncharacterized protein.
   
 0.700
KANK4
KN motif and ankyrin repeat domains 4.
    
 
 0.692
Your Current Organism:
Sus scrofa
NCBI taxonomy Id: 9823
Other names: S. scrofa, pig, pigs, swine, wild boar
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