STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DMP1Dentin matrix acidic phosphoprotein 1. (531 aa)    
Predicted Functional Partners:
ITGAV
Integrin subunit alpha V; Belongs to the integrin alpha chain family.
   
 
  0.903
ITGB3
Integrin beta; Belongs to the integrin beta chain family.
    
  0.902
MEPE
Matrix extracellular phosphoglycoprotein.
   
  
 0.821
SPP1
Osteopontin; Binds tightly to hydroxyapatite. Appears to form an integral part of the mineralized matrix. Probably important to cell-matrix interaction; Belongs to the osteopontin family.
  
  
 0.764
PHEX
Phosphate-regulating neutral endopeptidase isoform 1.
   
  
 0.751
ENAM
142 kDa enamelin; Involved in the mineralization and structural organization of enamel. Involved in the extension of enamel during the secretory stage of dental enamel formation.
  
  
 0.720
MGP
Matrix Gla protein; Associates with the organic matrix of bone and cartilage. Thought to act as an inhibitor of bone formation.
      
 0.713
FGF23
Fibroblast growth factor 23; Belongs to the heparin-binding growth factors family.
      
 0.706
RUNX2
Runt-related transcription factor 2 isoform a.
      
 0.664
SAP130
Sin3A associated protein 130.
      
 0.654
Your Current Organism:
Sus scrofa
NCBI taxonomy Id: 9823
Other names: S. scrofa, pig, pigs, swine, wild boar
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.