Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
SERPINE3Serpin family E member 3; Belongs to the serpin family. (408 aa)    
Predicted Functional Partners:
WDFY2
WD repeat and FYVE domain containing 2.
    
 
 0.784
FAM124A
Family with sequence similarity 124 member A.
 
    
 0.740
INTS6
Integrator complex subunit 6.
      
 0.732
AK8
Adenylate kinase 8; Belongs to the adenylate kinase family.
      
 0.702
ANKRD29
Ankyrin repeat domain 29.
    
 
 0.684
OLA1
Obg-like ATPase 1; Hydrolyzes ATP, and can also hydrolyze GTP with lower efficiency. Has lower affinity for GTP.
      
 0.652
RNF122
Ring finger protein 122.
    
 
 0.647
ST6GALNAC5
ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 5; Belongs to the glycosyltransferase 29 family.
    
 
 0.624
DUSP26
Dual specificity protein phosphatase; Dual specificity phosphatase able to dephosphorylate phosphotyrosine, phosphoserine and phosphothreonine residues, with a preference for phosphotyrosine as a substrate. Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily.
      
 0.623
GTF3C5
Uncharacterized protein.
      
 0.622
Your Current Organism:
Sus scrofa
NCBI taxonomy Id: 9823
Other names: S. scrofa, pig, pigs, swine, wild boar
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