Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
DLEU7Deleted in lymphocytic leukemia 7. (221 aa)    
Predicted Functional Partners:
KLHL35
Kelch like family member 35.
      
 0.766
CDH22
Cadherin 22; Cadherins are calcium-dependent cell adhesion proteins.
      
 0.702
ADAM30
ADAM metallopeptidase domain 30.
      
 0.700
ZNF189
Zinc finger protein 189.
      
 0.700
INSYN1
UPF0583 protein C15orf59 isoform 1.
      
 0.667
APOO
MICOS complex subunit; Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane.
      
 0.644
TPRN
Taperin.
      
 0.640
FAM124A
Family with sequence similarity 124 member A.
      
 0.638
DEGS2
Delta 4-desaturase, sphingolipid 2.
      
 0.637
CUEDC1
CUE domain-containing protein.
      
 0.627
Your Current Organism:
Sus scrofa
NCBI taxonomy Id: 9823
Other names: S. scrofa, pig, pigs, swine, wild boar
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