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The next version of STRING is ready for use in your analyses: updated networks across STRING newly available directed regulatory networks a new typed view showing functional, physical, and regulatory edges in one network new clustering options and cluster-based layouts … and much more!
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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CAB39LCalcium binding protein 39 like. (337 aa)    
Predicted Functional Partners:
STK11
Serine/threonine kinase 11; Belongs to the protein kinase superfamily.
    
 0.970
CAB39
Calcium-binding protein 39.
  
 
0.947
PRKAA1
Non-specific serine/threonine protein kinase.
    
 0.940
STRADA
STE20 related adaptor alpha.
    
 0.940
STRADB
STE20 related adaptor beta.
    
 0.935
PRKAA2
5'-AMP-activated protein kinase catalytic subunit alpha-2; Catalytic subunit of AMP-activated protein kinase (AMPK), an energy sensor protein kinase that plays a key role in regulating cellular energy metabolism. In response to reduction of intracellular ATP levels, AMPK activates energy-producing pathways and inhibits energy-consuming processes: inhibits protein, carbohydrate and lipid biosynthesis, as well as cell growth and proliferation. AMPK acts via direct phosphorylation of metabolic enzymes, and by longer-term effects via phosphorylation of transcription regulators. Also acts a [...]
    
 0.925
TMEM11
Transmembrane protein 11.
      
 0.779
STK24
Serine/threonine kinase 24.
    
 
 0.757
SBNO1
Protein strawberry notch homolog 1 isoform X1.
   
  
 0.728
TMEM117
Transmembrane protein 117 isoform X1.
      
 0.716
Your Current Organism:
Sus scrofa
NCBI taxonomy Id: 9823
Other names: S. scrofa, pig, pigs, swine, wild boar
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