Nodes:
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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co-expression
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[Homology]
Score
ESDS-formylglutathione hydrolase; Serine hydrolase involved in the detoxification of formaldehyde. (282 aa)    
Predicted Functional Partners:
ADH5
S-(hydroxymethyl)glutathione dehydrogenase; Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily.
 0.985
ADH1C
PKS_ER domain-containing protein.
 0.965
ADH4
Alcohol dehydrogenase 4 isoform 2.
 0.957
LOC110262184
Uncharacterized protein.
 0.937
A0A5G2QZY4_PIG
Uncharacterized protein.
  
 0.865
FSD2
Fibronectin type III and SPRY domain-containing protein 2 isoform X1.
    
 
 0.818
SORD
Sorbitol dehydrogenase; Polyol dehydrogenase that catalyzes the reversible NAD(+)- dependent oxidation of various sugar alcohols. Is active with xylitol, L-iditol and D-sorbitol (D-glucitol) as substrates, leading to the C2- oxidized products D-xylulose, L-sorbose and D-fructose, respectively (By similarity). Is a key enzyme in the polyol pathway that interconverts glucose and fructose via sorbitol, which constitutes an important alternate route for glucose metabolism. May play a role in sperm motility by using sorbitol as an alternative energy source for sperm motility (By similarity).
  
 
 0.788
GLO1
Lactoylglutathione lyase; Catalyzes the conversion of hemimercaptal, formed from methylglyoxal and glutathione, to S-lactoylglutathione.
  
 
 0.729
UAP1L1
UDP-N-acetylhexosamine pyrophosphorylase-like protein 1.
   
  
 0.705
SLC35F6
Solute carrier family 35 member F6; May play a role as a nucleotide-sugar transporter.
   
  
 0.684
Your Current Organism:
Sus scrofa
NCBI taxonomy Id: 9823
Other names: S. scrofa, pig, pigs, swine, wild boar
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