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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TNFSF11TNF superfamily member 11; Belongs to the tumor necrosis factor family. (319 aa)    
Predicted Functional Partners:
TNFRSF11A
TNF receptor superfamily member 11a.
    
 0.991
LTBR
Uncharacterized protein.
   
 0.839
CD40
Tumor necrosis factor receptor superfamily member 5; Receptor for TNFSF5/CD40LG (By similarity). Transduces TRAF6- and MAP3K8-mediated signals that activate ERK in macrophages and B cells, leading to induction of immunoglobulin secretion (By similarity).
   
 0.803
CST7
Cystatin domain-containing protein.
   
  
 0.742
TNFSF13B
Tumor necrosis factor superfamily member 13b; Belongs to the tumor necrosis factor family.
   
 0.725
TGFB2
Transforming growth factor beta-2 proprotein; Transforming growth factor beta-2 proprotein: Precursor of the Latency-associated peptide (LAP) and Transforming growth factor beta-2 (TGF-beta-2) chains, which constitute the regulatory and active subunit of TGF-beta-2, respectively. Transforming growth factor beta-2: Multifunctional protein that regulates various processes such as angiogenesis and heart development (By similarity). Activation into mature form follows different steps: following cleavage of the proprotein in the Golgi apparatus, Latency-associated peptide (LAP) and Transfor [...]
      
 0.691
LCK
Tyrosine-protein kinase.
   
 
 0.681
MATN2
Matrilin 2.
      
 0.675
TNFRSF18
TNFR-Cys domain-containing protein.
   
 
 0.658
TNFSF14
Tumor necrosis factor ligand superfamily member 14 isoform 1.
     
0.655
Your Current Organism:
Sus scrofa
NCBI taxonomy Id: 9823
Other names: S. scrofa, pig, pigs, swine, wild boar
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