STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
RGCCRegulator of cell cycle RGCC. (137 aa)    
Predicted Functional Partners:
EGLN1
Uncharacterized protein.
      
 0.547
EPAS1
Uncharacterized protein.
      
 0.541
GRIN2B
Glutamate ionotropic receptor NMDA type subunit 2B.
      
 0.541
ZNF644
Zinc finger protein 644.
      
 0.536
CUL7
Cullin-7 isoform X6; Belongs to the cullin family.
      
 0.495
HFM1
Helicase for meiosis 1.
      
 0.476
SPINK5
Serine peptidase inhibitor, Kazal type 5.
      
 0.468
HOPX
Homeodomain-only protein; Atypical homeodomain protein which does not bind DNA and is required to modulate cardiac growth and development. Acts via its interaction with SRF, thereby modulating the expression of SRF- dependent cardiac-specific genes and cardiac development. Prevents SRF- dependent transcription either by inhibiting SRF binding to DNA or by recruiting histone deacetylase (HDAC) proteins that prevent transcription by SRF. Overexpression causes cardiac hypertrophy. Acts as a co-chaperone for HSPA1A and HSPA1B chaperone proteins and assists in chaperone-mediated protein ref [...]
      
 0.468
NRROS
Negative regulator of reactive oxygen species.
      
 0.453
NPFFR2
Neuropeptide FF receptor 2; Belongs to the G-protein coupled receptor 1 family.
      
 0.452
Your Current Organism:
Sus scrofa
NCBI taxonomy Id: 9823
Other names: S. scrofa, pig, pigs, swine, wild boar
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.