MTRF1 protein (Sus scrofa) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Input:

Neighborhood

Gene Fusion

Co-occurrence

Co-expression

Experiments

Databases

Textmining

[Homology]

Score

MTRF1

Mitochondrial translation release factor 1. (446 aa)

Predicted Functional Partners:

MRPS11

0.937

MRPL58

0.920

GFM2

0.902

MRPL35

0.893

N6AMT1

0.872

MRPS7

0.767

MRPS2

0.747

HEMK1

0.737

MRPL13

0.735

MRRF

0.729

Your Current Organism:

Sus scrofa

NCBI taxonomy Id: 9823
Other names: S. scrofa, pig, pigs, swine, wild boar

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc.

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
GFM2	MRPL13	ENSSSCP00000040683	ENSSSCP00000029628	Ribosome-releasing factor 2, mitochondrial; Mitochondrial GTPase that mediates the disassembly of ribosomes from messenger RNA at the termination of mitochondrial protein biosynthesis. Acts in collaboration with MRRF. GTP hydrolysis follows the ribosome disassembly and probably occurs on the ribosome large subunit. Not involved in the GTP-dependent ribosomal translocation step during translation elongation; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.	39S ribosomal protein L13, mitochondrial; Belongs to the universal ribosomal protein uL13 family.	0.741
GFM2	MRPL35	ENSSSCP00000040683	ENSSSCP00000032438	Ribosome-releasing factor 2, mitochondrial; Mitochondrial GTPase that mediates the disassembly of ribosomes from messenger RNA at the termination of mitochondrial protein biosynthesis. Acts in collaboration with MRRF. GTP hydrolysis follows the ribosome disassembly and probably occurs on the ribosome large subunit. Not involved in the GTP-dependent ribosomal translocation step during translation elongation; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.	39S ribosomal protein L35, mitochondrial isoform X1.	0.564
GFM2	MRPL58	ENSSSCP00000040683	ENSSSCP00000031800	Ribosome-releasing factor 2, mitochondrial; Mitochondrial GTPase that mediates the disassembly of ribosomes from messenger RNA at the termination of mitochondrial protein biosynthesis. Acts in collaboration with MRRF. GTP hydrolysis follows the ribosome disassembly and probably occurs on the ribosome large subunit. Not involved in the GTP-dependent ribosomal translocation step during translation elongation; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.	Peptidyl-tRNA hydrolase ICT1, mitochondrial isoform 1.	0.746
GFM2	MRPS11	ENSSSCP00000040683	ENSSSCP00000031627	Ribosome-releasing factor 2, mitochondrial; Mitochondrial GTPase that mediates the disassembly of ribosomes from messenger RNA at the termination of mitochondrial protein biosynthesis. Acts in collaboration with MRRF. GTP hydrolysis follows the ribosome disassembly and probably occurs on the ribosome large subunit. Not involved in the GTP-dependent ribosomal translocation step during translation elongation; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.	Mitochondrial ribosomal protein S11; Belongs to the universal ribosomal protein uS11 family.	0.496
GFM2	MRPS7	ENSSSCP00000040683	ENSSSCP00000031553	Ribosome-releasing factor 2, mitochondrial; Mitochondrial GTPase that mediates the disassembly of ribosomes from messenger RNA at the termination of mitochondrial protein biosynthesis. Acts in collaboration with MRRF. GTP hydrolysis follows the ribosome disassembly and probably occurs on the ribosome large subunit. Not involved in the GTP-dependent ribosomal translocation step during translation elongation; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.	28S ribosomal protein S7, mitochondrial.	0.530
GFM2	MRRF	ENSSSCP00000040683	ENSSSCP00000005928	Ribosome-releasing factor 2, mitochondrial; Mitochondrial GTPase that mediates the disassembly of ribosomes from messenger RNA at the termination of mitochondrial protein biosynthesis. Acts in collaboration with MRRF. GTP hydrolysis follows the ribosome disassembly and probably occurs on the ribosome large subunit. Not involved in the GTP-dependent ribosomal translocation step during translation elongation; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.	Ribosome-recycling factor, mitochondrial isoform 1.	0.907
GFM2	MTRF1	ENSSSCP00000040683	ENSSSCP00000010075	Ribosome-releasing factor 2, mitochondrial; Mitochondrial GTPase that mediates the disassembly of ribosomes from messenger RNA at the termination of mitochondrial protein biosynthesis. Acts in collaboration with MRRF. GTP hydrolysis follows the ribosome disassembly and probably occurs on the ribosome large subunit. Not involved in the GTP-dependent ribosomal translocation step during translation elongation; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.	Mitochondrial translation release factor 1.	0.902
HEMK1	MTRF1	ENSSSCP00000024827	ENSSSCP00000010075	HemK methyltransferase family member 1.	Mitochondrial translation release factor 1.	0.737
HEMK1	N6AMT1	ENSSSCP00000024827	ENSSSCP00000020458	HemK methyltransferase family member 1.	N-6 adenine-specific DNA methyltransferase 1.	0.466
MRPL13	GFM2	ENSSSCP00000029628	ENSSSCP00000040683	39S ribosomal protein L13, mitochondrial; Belongs to the universal ribosomal protein uL13 family.	Ribosome-releasing factor 2, mitochondrial; Mitochondrial GTPase that mediates the disassembly of ribosomes from messenger RNA at the termination of mitochondrial protein biosynthesis. Acts in collaboration with MRRF. GTP hydrolysis follows the ribosome disassembly and probably occurs on the ribosome large subunit. Not involved in the GTP-dependent ribosomal translocation step during translation elongation; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.	0.741
MRPL13	MRPL35	ENSSSCP00000029628	ENSSSCP00000032438	39S ribosomal protein L13, mitochondrial; Belongs to the universal ribosomal protein uL13 family.	39S ribosomal protein L35, mitochondrial isoform X1.	0.979
MRPL13	MRPL58	ENSSSCP00000029628	ENSSSCP00000031800	39S ribosomal protein L13, mitochondrial; Belongs to the universal ribosomal protein uL13 family.	Peptidyl-tRNA hydrolase ICT1, mitochondrial isoform 1.	0.984
MRPL13	MRPS11	ENSSSCP00000029628	ENSSSCP00000031627	39S ribosomal protein L13, mitochondrial; Belongs to the universal ribosomal protein uL13 family.	Mitochondrial ribosomal protein S11; Belongs to the universal ribosomal protein uS11 family.	0.984
MRPL13	MRPS2	ENSSSCP00000029628	ENSSSCP00000074362	39S ribosomal protein L13, mitochondrial; Belongs to the universal ribosomal protein uL13 family.	Mitochondrial ribosomal protein S2.	0.962
MRPL13	MRPS7	ENSSSCP00000029628	ENSSSCP00000031553	39S ribosomal protein L13, mitochondrial; Belongs to the universal ribosomal protein uL13 family.	28S ribosomal protein S7, mitochondrial.	0.974
MRPL13	MRRF	ENSSSCP00000029628	ENSSSCP00000005928	39S ribosomal protein L13, mitochondrial; Belongs to the universal ribosomal protein uL13 family.	Ribosome-recycling factor, mitochondrial isoform 1.	0.736
MRPL13	MTRF1	ENSSSCP00000029628	ENSSSCP00000010075	39S ribosomal protein L13, mitochondrial; Belongs to the universal ribosomal protein uL13 family.	Mitochondrial translation release factor 1.	0.735
MRPL35	GFM2	ENSSSCP00000032438	ENSSSCP00000040683	39S ribosomal protein L35, mitochondrial isoform X1.	Ribosome-releasing factor 2, mitochondrial; Mitochondrial GTPase that mediates the disassembly of ribosomes from messenger RNA at the termination of mitochondrial protein biosynthesis. Acts in collaboration with MRRF. GTP hydrolysis follows the ribosome disassembly and probably occurs on the ribosome large subunit. Not involved in the GTP-dependent ribosomal translocation step during translation elongation; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.	0.564
MRPL35	MRPL13	ENSSSCP00000032438	ENSSSCP00000029628	39S ribosomal protein L35, mitochondrial isoform X1.	39S ribosomal protein L13, mitochondrial; Belongs to the universal ribosomal protein uL13 family.	0.979
MRPL35	MRPL58	ENSSSCP00000032438	ENSSSCP00000031800	39S ribosomal protein L35, mitochondrial isoform X1.	Peptidyl-tRNA hydrolase ICT1, mitochondrial isoform 1.	0.876