STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AUHMethylglutaconyl-CoA hydratase, mitochondrial isoform X1; Belongs to the enoyl-CoA hydratase/isomerase family. (338 aa)    
Predicted Functional Partners:
HADH
Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial; Plays an essential role in the mitochondrial beta-oxidation of short chain fatty acids. Exerts it highest activity toward 3- hydroxybutyryl-CoA; Belongs to the 3-hydroxyacyl-CoA dehydrogenase family.
 0.978
HMGCLL1
3-hydroxymethyl-3-methylglutaryl-CoA lyase like 1.
 
 
 0.966
MCCC1
Methylcrotonoyl-CoA carboxylase 1.
  
 0.945
HMGCS1
3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase.
  
 
 0.939
HMGCS2
Hydroxymethylglutaryl-CoA synthase, mitochondrial; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase; Belongs to the thiolase-like superfamily. HMG-CoA synthase family.
  
 
 0.939
HSDL2
Hydroxysteroid dehydrogenase like 2.
  
 0.845
HMGCL
3-hydroxy-3-methylglutaryl-CoA lyase.
 
 
 0.790
ACAA1
Acetyl-CoA acyltransferase 1; Belongs to the thiolase-like superfamily. Thiolase family.
  
 0.741
APMAP
Adipocyte plasma membrane associated protein.
      
 0.731
DECR1
Uncharacterized protein.
   
 0.717
Your Current Organism:
Sus scrofa
NCBI taxonomy Id: 9823
Other names: S. scrofa, pig, pigs, swine, wild boar
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.