| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| CDC42 | CRK | ENSSSCP00000029815 | ENSSSCP00000034913 | Cell division control protein 42 homolog; Plasma membrane-associated small GTPase which cycles between an active GTP-bound and an inactive GDP-bound state. In active state binds to a variety of effector proteins to regulate cellular responses. Involved in epithelial cell polarization processes. Regulates the bipolar attachment of spindle microtubules to kinetochores before chromosome congression in metaphase. Regulates cell migration. In neurons, plays a role in the extension and maintenance of the formation of filopodia, thin and actin-rich surface projections (By similarity). Require [...] | CRK proto-oncogene, adaptor protein. | 0.494 |
| CDC42 | DOCK5 | ENSSSCP00000029815 | ENSSSCP00000010303 | Cell division control protein 42 homolog; Plasma membrane-associated small GTPase which cycles between an active GTP-bound and an inactive GDP-bound state. In active state binds to a variety of effector proteins to regulate cellular responses. Involved in epithelial cell polarization processes. Regulates the bipolar attachment of spindle microtubules to kinetochores before chromosome congression in metaphase. Regulates cell migration. In neurons, plays a role in the extension and maintenance of the formation of filopodia, thin and actin-rich surface projections (By similarity). Require [...] | Dedicator of cytokinesis 5; Belongs to the DOCK family. | 0.635 |
| CDC42 | ELMO2 | ENSSSCP00000029815 | ENSSSCP00000027586 | Cell division control protein 42 homolog; Plasma membrane-associated small GTPase which cycles between an active GTP-bound and an inactive GDP-bound state. In active state binds to a variety of effector proteins to regulate cellular responses. Involved in epithelial cell polarization processes. Regulates the bipolar attachment of spindle microtubules to kinetochores before chromosome congression in metaphase. Regulates cell migration. In neurons, plays a role in the extension and maintenance of the formation of filopodia, thin and actin-rich surface projections (By similarity). Require [...] | Engulfment and cell motility 2. | 0.603 |
| CDC42 | FMN1 | ENSSSCP00000029815 | ENSSSCP00000053085 | Cell division control protein 42 homolog; Plasma membrane-associated small GTPase which cycles between an active GTP-bound and an inactive GDP-bound state. In active state binds to a variety of effector proteins to regulate cellular responses. Involved in epithelial cell polarization processes. Regulates the bipolar attachment of spindle microtubules to kinetochores before chromosome congression in metaphase. Regulates cell migration. In neurons, plays a role in the extension and maintenance of the formation of filopodia, thin and actin-rich surface projections (By similarity). Require [...] | Formin 1. | 0.502 |
| CDC42 | RAC1 | ENSSSCP00000029815 | ENSSSCP00000062132 | Cell division control protein 42 homolog; Plasma membrane-associated small GTPase which cycles between an active GTP-bound and an inactive GDP-bound state. In active state binds to a variety of effector proteins to regulate cellular responses. Involved in epithelial cell polarization processes. Regulates the bipolar attachment of spindle microtubules to kinetochores before chromosome congression in metaphase. Regulates cell migration. In neurons, plays a role in the extension and maintenance of the formation of filopodia, thin and actin-rich surface projections (By similarity). Require [...] | Rac family small GTPase 1. | 0.783 |
| CDC42 | RAC2 | ENSSSCP00000029815 | ENSSSCP00000070230 | Cell division control protein 42 homolog; Plasma membrane-associated small GTPase which cycles between an active GTP-bound and an inactive GDP-bound state. In active state binds to a variety of effector proteins to regulate cellular responses. Involved in epithelial cell polarization processes. Regulates the bipolar attachment of spindle microtubules to kinetochores before chromosome congression in metaphase. Regulates cell migration. In neurons, plays a role in the extension and maintenance of the formation of filopodia, thin and actin-rich surface projections (By similarity). Require [...] | Rac family small GTPase 2. | 0.931 |
| CDC42 | RHOG | ENSSSCP00000029815 | ENSSSCP00000051183 | Cell division control protein 42 homolog; Plasma membrane-associated small GTPase which cycles between an active GTP-bound and an inactive GDP-bound state. In active state binds to a variety of effector proteins to regulate cellular responses. Involved in epithelial cell polarization processes. Regulates the bipolar attachment of spindle microtubules to kinetochores before chromosome congression in metaphase. Regulates cell migration. In neurons, plays a role in the extension and maintenance of the formation of filopodia, thin and actin-rich surface projections (By similarity). Require [...] | Uncharacterized protein. | 0.540 |
| CRK | CDC42 | ENSSSCP00000034913 | ENSSSCP00000029815 | CRK proto-oncogene, adaptor protein. | Cell division control protein 42 homolog; Plasma membrane-associated small GTPase which cycles between an active GTP-bound and an inactive GDP-bound state. In active state binds to a variety of effector proteins to regulate cellular responses. Involved in epithelial cell polarization processes. Regulates the bipolar attachment of spindle microtubules to kinetochores before chromosome congression in metaphase. Regulates cell migration. In neurons, plays a role in the extension and maintenance of the formation of filopodia, thin and actin-rich surface projections (By similarity). Require [...] | 0.494 |
| CRK | DOCK5 | ENSSSCP00000034913 | ENSSSCP00000010303 | CRK proto-oncogene, adaptor protein. | Dedicator of cytokinesis 5; Belongs to the DOCK family. | 0.666 |
| CRK | ELMO2 | ENSSSCP00000034913 | ENSSSCP00000027586 | CRK proto-oncogene, adaptor protein. | Engulfment and cell motility 2. | 0.949 |
| CRK | ELMO3 | ENSSSCP00000034913 | ENSSSCP00000003005 | CRK proto-oncogene, adaptor protein. | Engulfment and cell motility 3. | 0.532 |
| CRK | RAC1 | ENSSSCP00000034913 | ENSSSCP00000062132 | CRK proto-oncogene, adaptor protein. | Rac family small GTPase 1. | 0.563 |
| DOCK5 | CDC42 | ENSSSCP00000010303 | ENSSSCP00000029815 | Dedicator of cytokinesis 5; Belongs to the DOCK family. | Cell division control protein 42 homolog; Plasma membrane-associated small GTPase which cycles between an active GTP-bound and an inactive GDP-bound state. In active state binds to a variety of effector proteins to regulate cellular responses. Involved in epithelial cell polarization processes. Regulates the bipolar attachment of spindle microtubules to kinetochores before chromosome congression in metaphase. Regulates cell migration. In neurons, plays a role in the extension and maintenance of the formation of filopodia, thin and actin-rich surface projections (By similarity). Require [...] | 0.635 |
| DOCK5 | CRK | ENSSSCP00000010303 | ENSSSCP00000034913 | Dedicator of cytokinesis 5; Belongs to the DOCK family. | CRK proto-oncogene, adaptor protein. | 0.666 |
| DOCK5 | ELMO2 | ENSSSCP00000010303 | ENSSSCP00000027586 | Dedicator of cytokinesis 5; Belongs to the DOCK family. | Engulfment and cell motility 2. | 0.839 |
| DOCK5 | ELMO3 | ENSSSCP00000010303 | ENSSSCP00000003005 | Dedicator of cytokinesis 5; Belongs to the DOCK family. | Engulfment and cell motility 3. | 0.786 |
| DOCK5 | FMN1 | ENSSSCP00000010303 | ENSSSCP00000053085 | Dedicator of cytokinesis 5; Belongs to the DOCK family. | Formin 1. | 0.631 |
| DOCK5 | IRF2BP1 | ENSSSCP00000010303 | ENSSSCP00000003347 | Dedicator of cytokinesis 5; Belongs to the DOCK family. | Interferon regulatory factor 2 binding protein 1. | 0.750 |
| DOCK5 | RAC1 | ENSSSCP00000010303 | ENSSSCP00000062132 | Dedicator of cytokinesis 5; Belongs to the DOCK family. | Rac family small GTPase 1. | 0.768 |
| DOCK5 | RAC2 | ENSSSCP00000010303 | ENSSSCP00000070230 | Dedicator of cytokinesis 5; Belongs to the DOCK family. | Rac family small GTPase 2. | 0.641 |