node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
DRD2 | PPP2CA | ENSSSCP00000049999 | ENSSSCP00000015208 | Dopamine receptor D2; Belongs to the G-protein coupled receptor 1 family. | Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform; PP2A is the major phosphatase for microtubule-associated proteins (MAPs). PP2A can modulate the activity of phosphorylase B kinase casein kinase 2, mitogen-stimulated S6 kinase, and MAP-2 kinase. Cooperates with SGO2 to protect centromeric cohesin from separase- mediated cleavage in oocytes specifically during meiosis I. Activates RAF1 by dephosphorylating it at 'Ser-259' (By similarity). | 0.910 |
DRD2 | PPP2CB | ENSSSCP00000049999 | ENSSSCP00000072937 | Dopamine receptor D2; Belongs to the G-protein coupled receptor 1 family. | Serine/threonine-protein phosphatase. | 0.909 |
DRD2 | PPP2R1A | ENSSSCP00000049999 | ENSSSCP00000053789 | Dopamine receptor D2; Belongs to the G-protein coupled receptor 1 family. | Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform. | 0.908 |
DRD2 | PPP2R1B | ENSSSCP00000049999 | ENSSSCP00000020079 | Dopamine receptor D2; Belongs to the G-protein coupled receptor 1 family. | Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A beta isoform; The PR65 subunit of protein phosphatase 2A serves as a scaffolding molecule to coordinate the assembly of the catalytic subunit and a variable regulatory B subunit. | 0.904 |
DRD2 | PPP2R2A | ENSSSCP00000049999 | ENSSSCP00000010312 | Dopamine receptor D2; Belongs to the G-protein coupled receptor 1 family. | Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B alpha isoform; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. | 0.911 |
DRD2 | PPP2R2C | ENSSSCP00000049999 | ENSSSCP00000009286 | Dopamine receptor D2; Belongs to the G-protein coupled receptor 1 family. | Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B; Belongs to the phosphatase 2A regulatory subunit B family. | 0.900 |
DRD2 | PPP2R5A | ENSSSCP00000049999 | ENSSSCP00000016538 | Dopamine receptor D2; Belongs to the G-protein coupled receptor 1 family. | Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. | 0.914 |
DRD2 | PPP2R5E | ENSSSCP00000049999 | ENSSSCP00000050867 | Dopamine receptor D2; Belongs to the G-protein coupled receptor 1 family. | Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. | 0.902 |
IRAK1 | IRAK4 | ENSSSCP00000013604 | ENSSSCP00000000849 | Interleukin 1 receptor associated kinase 1. | Protein kinase domain-containing protein. | 0.998 |
IRAK1 | PPP2CA | ENSSSCP00000013604 | ENSSSCP00000015208 | Interleukin 1 receptor associated kinase 1. | Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform; PP2A is the major phosphatase for microtubule-associated proteins (MAPs). PP2A can modulate the activity of phosphorylase B kinase casein kinase 2, mitogen-stimulated S6 kinase, and MAP-2 kinase. Cooperates with SGO2 to protect centromeric cohesin from separase- mediated cleavage in oocytes specifically during meiosis I. Activates RAF1 by dephosphorylating it at 'Ser-259' (By similarity). | 0.929 |
IRAK1 | PPP2CB | ENSSSCP00000013604 | ENSSSCP00000072937 | Interleukin 1 receptor associated kinase 1. | Serine/threonine-protein phosphatase. | 0.924 |
IRAK1 | PPP2R1A | ENSSSCP00000013604 | ENSSSCP00000053789 | Interleukin 1 receptor associated kinase 1. | Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform. | 0.910 |
IRAK1 | PPP2R1B | ENSSSCP00000013604 | ENSSSCP00000020079 | Interleukin 1 receptor associated kinase 1. | Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A beta isoform; The PR65 subunit of protein phosphatase 2A serves as a scaffolding molecule to coordinate the assembly of the catalytic subunit and a variable regulatory B subunit. | 0.910 |
IRAK1 | PPP2R2A | ENSSSCP00000013604 | ENSSSCP00000010312 | Interleukin 1 receptor associated kinase 1. | Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B alpha isoform; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. | 0.913 |
IRAK1 | PPP2R2C | ENSSSCP00000013604 | ENSSSCP00000009286 | Interleukin 1 receptor associated kinase 1. | Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B; Belongs to the phosphatase 2A regulatory subunit B family. | 0.900 |
IRAK4 | IRAK1 | ENSSSCP00000000849 | ENSSSCP00000013604 | Protein kinase domain-containing protein. | Interleukin 1 receptor associated kinase 1. | 0.998 |
IRAK4 | PPP2CA | ENSSSCP00000000849 | ENSSSCP00000015208 | Protein kinase domain-containing protein. | Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform; PP2A is the major phosphatase for microtubule-associated proteins (MAPs). PP2A can modulate the activity of phosphorylase B kinase casein kinase 2, mitogen-stimulated S6 kinase, and MAP-2 kinase. Cooperates with SGO2 to protect centromeric cohesin from separase- mediated cleavage in oocytes specifically during meiosis I. Activates RAF1 by dephosphorylating it at 'Ser-259' (By similarity). | 0.916 |
IRAK4 | PPP2CB | ENSSSCP00000000849 | ENSSSCP00000072937 | Protein kinase domain-containing protein. | Serine/threonine-protein phosphatase. | 0.913 |
IRAK4 | PPP2R1A | ENSSSCP00000000849 | ENSSSCP00000053789 | Protein kinase domain-containing protein. | Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform. | 0.907 |
IRAK4 | PPP2R1B | ENSSSCP00000000849 | ENSSSCP00000020079 | Protein kinase domain-containing protein. | Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A beta isoform; The PR65 subunit of protein phosphatase 2A serves as a scaffolding molecule to coordinate the assembly of the catalytic subunit and a variable regulatory B subunit. | 0.911 |