Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
PBKLymphokine-activated killer T-cell-originated protein kinase isoform X1. (322 aa)    
Predicted Functional Partners:
CDK1
Cyclin-dependent kinase 1 isoform 1; Belongs to the protein kinase superfamily.
   
 0.989
NUF2
NUF2 component of NDC80 kinetochore complex.
   
  
 0.970
NDC80
NDC80 kinetochore complex component.
   
 
 0.965
MELK
Non-specific serine/threonine protein kinase.
   
 0.964
TTK
TTK protein kinase.
   
 
 0.960
TOP2A
DNA topoisomerase 2-alpha; Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double- strand breaks. Essential during mitosis and meiosis for proper segregation of daughter chromosomes. May play a role in regulating the period length of ARNTL/BMAL1 transcriptional oscillation.
   
  
 0.957
KIF11
Kinesin-like protein KIF11; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.
   
  
 0.956
NUSAP1
Uncharacterized protein.
   
  
 0.956
CDCA3
Cell division cycle-associated protein 3 isoform 1.
   
  
 0.952
DLGAP5
DLG associated protein 5.
   
  
 0.952
Your Current Organism:
Sus scrofa
NCBI taxonomy Id: 9823
Other names: S. scrofa, pig, pigs, swine, wild boar
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