STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SPOCK3SPARC (osteonectin), cwcv and kazal like domains proteoglycan 3. (436 aa)    
Predicted Functional Partners:
RAB3IL1
RAB3A interacting protein like 1.
      
 0.534
MLLT6
MLLT6, PHD finger containing.
      
 0.509
DYNLL1
Dynein light chain.
   
  
 0.502
FSTL4
Follistatin like 4.
   
  
0.502
MMP14
Matrix metalloproteinase-14; Endopeptidase that degrades various components of the extracellular matrix, such as collagen. Activates progelatinase A. Essential for pericellular collagenolysis and modeling of skeletal and extraskeletal connective tissues during development. May be involved in actin cytoskeleton reorganization by cleaving PTK7. Acts as a positive regulator of cell growth and migration via activation of MMP15 in association with pro-MMP2. Involved in the formation of the fibrovascular tissues in association with pro-MMP2. Cleaves ADGRB1 to release vasculostatin-40 which i [...]
    
 0.491
ZBTB1
Zinc finger and BTB domain-containing protein 1 isoform X1.
      
 0.491
DENND5B
DENN domain containing 5B.
      
 0.487
GNAZ
Guanine nucleotide-binding protein G(Z) subunit alpha isoform X1.
      
 0.485
LOC100518097
SH2 domain-containing protein.
      
 0.473
LOC100737676
Uncharacterized protein.
      
 0.473
Your Current Organism:
Sus scrofa
NCBI taxonomy Id: 9823
Other names: S. scrofa, pig, pigs, swine, wild boar
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.