node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ABCA1 | ABCG1 | ENSSSCP00000005818 | ENSSSCP00000053363 | Uncharacterized protein. | ATP binding cassette subfamily G member 1. | 0.538 |
ABCA1 | APOA1 | ENSSSCP00000005818 | ENSSSCP00000033805 | Uncharacterized protein. | Truncated apolipoprotein A-I; Participates in the reverse transport of cholesterol from tissues to the liver for excretion by promoting cholesterol efflux from tissues and by acting as a cofactor for the lecithin cholesterol acyltransferase (LCAT). As part of the SPAP complex, activates spermatozoa motility; Belongs to the apolipoprotein A1/A4/E family. | 0.996 |
ABCA1 | APOB | ENSSSCP00000005818 | ENSSSCP00000042786 | Uncharacterized protein. | Apolipoprotein B-100. | 0.738 |
ABCA1 | APOE | ENSSSCP00000005818 | ENSSSCP00000003343 | Uncharacterized protein. | Apolipoprotein E; APOE is an apolipoprotein, a protein associating with lipid particles, that mainly functions in lipoprotein-mediated lipid transport between organs via the plasma and interstitial fluids. APOE is a core component of plasma lipoproteins and is involved in their production, conversion and clearance. Apoliproteins are amphipathic molecules that interact both with lipids of the lipoprotein particle core and the aqueous environment of the plasma. As such, APOE associates with chylomicrons, chylomicron remnants, very low density lipoproteins (VLDL) and intermediate density [...] | 0.912 |
ABCA1 | SCARB1 | ENSSSCP00000005818 | ENSSSCP00000010421 | Uncharacterized protein. | Scavenger receptor class B member 1; Receptor for different ligands such as phospholipids, cholesterol ester, lipoproteins, phosphatidylserine and apoptotic cells. Receptor for HDL, mediating selective uptake of cholesteryl ether and HDL-dependent cholesterol efflux. Also facilitates the flux of free and esterified cholesterol between the cell surface and apoB- containing lipoproteins and modified lipoproteins, although less efficiently than HDL. May be involved in the phagocytosis of apoptotic cells, via its phosphatidylserine binding activity. | 0.861 |
ABCG1 | ABCA1 | ENSSSCP00000053363 | ENSSSCP00000005818 | ATP binding cassette subfamily G member 1. | Uncharacterized protein. | 0.538 |
ABCG1 | APOA1 | ENSSSCP00000053363 | ENSSSCP00000033805 | ATP binding cassette subfamily G member 1. | Truncated apolipoprotein A-I; Participates in the reverse transport of cholesterol from tissues to the liver for excretion by promoting cholesterol efflux from tissues and by acting as a cofactor for the lecithin cholesterol acyltransferase (LCAT). As part of the SPAP complex, activates spermatozoa motility; Belongs to the apolipoprotein A1/A4/E family. | 0.821 |
ABCG1 | APOB | ENSSSCP00000053363 | ENSSSCP00000042786 | ATP binding cassette subfamily G member 1. | Apolipoprotein B-100. | 0.577 |
ABCG1 | APOE | ENSSSCP00000053363 | ENSSSCP00000003343 | ATP binding cassette subfamily G member 1. | Apolipoprotein E; APOE is an apolipoprotein, a protein associating with lipid particles, that mainly functions in lipoprotein-mediated lipid transport between organs via the plasma and interstitial fluids. APOE is a core component of plasma lipoproteins and is involved in their production, conversion and clearance. Apoliproteins are amphipathic molecules that interact both with lipids of the lipoprotein particle core and the aqueous environment of the plasma. As such, APOE associates with chylomicrons, chylomicron remnants, very low density lipoproteins (VLDL) and intermediate density [...] | 0.793 |
ABCG1 | SCARB1 | ENSSSCP00000053363 | ENSSSCP00000010421 | ATP binding cassette subfamily G member 1. | Scavenger receptor class B member 1; Receptor for different ligands such as phospholipids, cholesterol ester, lipoproteins, phosphatidylserine and apoptotic cells. Receptor for HDL, mediating selective uptake of cholesteryl ether and HDL-dependent cholesterol efflux. Also facilitates the flux of free and esterified cholesterol between the cell surface and apoB- containing lipoproteins and modified lipoproteins, although less efficiently than HDL. May be involved in the phagocytosis of apoptotic cells, via its phosphatidylserine binding activity. | 0.830 |
APOA1 | ABCA1 | ENSSSCP00000033805 | ENSSSCP00000005818 | Truncated apolipoprotein A-I; Participates in the reverse transport of cholesterol from tissues to the liver for excretion by promoting cholesterol efflux from tissues and by acting as a cofactor for the lecithin cholesterol acyltransferase (LCAT). As part of the SPAP complex, activates spermatozoa motility; Belongs to the apolipoprotein A1/A4/E family. | Uncharacterized protein. | 0.996 |
APOA1 | ABCG1 | ENSSSCP00000033805 | ENSSSCP00000053363 | Truncated apolipoprotein A-I; Participates in the reverse transport of cholesterol from tissues to the liver for excretion by promoting cholesterol efflux from tissues and by acting as a cofactor for the lecithin cholesterol acyltransferase (LCAT). As part of the SPAP complex, activates spermatozoa motility; Belongs to the apolipoprotein A1/A4/E family. | ATP binding cassette subfamily G member 1. | 0.821 |
APOA1 | APOB | ENSSSCP00000033805 | ENSSSCP00000042786 | Truncated apolipoprotein A-I; Participates in the reverse transport of cholesterol from tissues to the liver for excretion by promoting cholesterol efflux from tissues and by acting as a cofactor for the lecithin cholesterol acyltransferase (LCAT). As part of the SPAP complex, activates spermatozoa motility; Belongs to the apolipoprotein A1/A4/E family. | Apolipoprotein B-100. | 0.994 |
APOA1 | APOE | ENSSSCP00000033805 | ENSSSCP00000003343 | Truncated apolipoprotein A-I; Participates in the reverse transport of cholesterol from tissues to the liver for excretion by promoting cholesterol efflux from tissues and by acting as a cofactor for the lecithin cholesterol acyltransferase (LCAT). As part of the SPAP complex, activates spermatozoa motility; Belongs to the apolipoprotein A1/A4/E family. | Apolipoprotein E; APOE is an apolipoprotein, a protein associating with lipid particles, that mainly functions in lipoprotein-mediated lipid transport between organs via the plasma and interstitial fluids. APOE is a core component of plasma lipoproteins and is involved in their production, conversion and clearance. Apoliproteins are amphipathic molecules that interact both with lipids of the lipoprotein particle core and the aqueous environment of the plasma. As such, APOE associates with chylomicrons, chylomicron remnants, very low density lipoproteins (VLDL) and intermediate density [...] | 0.988 |
APOA1 | SCARB1 | ENSSSCP00000033805 | ENSSSCP00000010421 | Truncated apolipoprotein A-I; Participates in the reverse transport of cholesterol from tissues to the liver for excretion by promoting cholesterol efflux from tissues and by acting as a cofactor for the lecithin cholesterol acyltransferase (LCAT). As part of the SPAP complex, activates spermatozoa motility; Belongs to the apolipoprotein A1/A4/E family. | Scavenger receptor class B member 1; Receptor for different ligands such as phospholipids, cholesterol ester, lipoproteins, phosphatidylserine and apoptotic cells. Receptor for HDL, mediating selective uptake of cholesteryl ether and HDL-dependent cholesterol efflux. Also facilitates the flux of free and esterified cholesterol between the cell surface and apoB- containing lipoproteins and modified lipoproteins, although less efficiently than HDL. May be involved in the phagocytosis of apoptotic cells, via its phosphatidylserine binding activity. | 0.988 |
APOB | ABCA1 | ENSSSCP00000042786 | ENSSSCP00000005818 | Apolipoprotein B-100. | Uncharacterized protein. | 0.738 |
APOB | ABCG1 | ENSSSCP00000042786 | ENSSSCP00000053363 | Apolipoprotein B-100. | ATP binding cassette subfamily G member 1. | 0.577 |
APOB | APOA1 | ENSSSCP00000042786 | ENSSSCP00000033805 | Apolipoprotein B-100. | Truncated apolipoprotein A-I; Participates in the reverse transport of cholesterol from tissues to the liver for excretion by promoting cholesterol efflux from tissues and by acting as a cofactor for the lecithin cholesterol acyltransferase (LCAT). As part of the SPAP complex, activates spermatozoa motility; Belongs to the apolipoprotein A1/A4/E family. | 0.994 |
APOB | APOE | ENSSSCP00000042786 | ENSSSCP00000003343 | Apolipoprotein B-100. | Apolipoprotein E; APOE is an apolipoprotein, a protein associating with lipid particles, that mainly functions in lipoprotein-mediated lipid transport between organs via the plasma and interstitial fluids. APOE is a core component of plasma lipoproteins and is involved in their production, conversion and clearance. Apoliproteins are amphipathic molecules that interact both with lipids of the lipoprotein particle core and the aqueous environment of the plasma. As such, APOE associates with chylomicrons, chylomicron remnants, very low density lipoproteins (VLDL) and intermediate density [...] | 0.988 |
APOB | CD81 | ENSSSCP00000042786 | ENSSSCP00000073970 | Apolipoprotein B-100. | Tetraspanin. | 0.400 |