DIABLO protein (Sus scrofa) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Input:

Neighborhood

Gene fusion

Co-occurrence

Co-expression

Experiments

Databases

Textmining

[Homology]

Score

DIABLO

Uncharacterized protein. (237 aa)

Predicted Functional Partners:

XIAP

0.997

BIRC3

0.982

BIRC5

0.980

BIRC6

0.878

BIRC7

0.874

BIRC7-2

0.874

CASP9

0.838

CASP7

0.836

BAK1

0.824

HTRA2

0.786

Your Current Organism:

Sus scrofa

NCBI taxonomy Id: 9823
Other names: S. scrofa, pig, pigs, swine, wild boar

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc.

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
BAK1	CASP7	ENSSSCP00000032742	ENSSSCP00000043126	Uncharacterized protein.	Caspase 7; Belongs to the peptidase C14A family.	0.553
BAK1	CASP9	ENSSSCP00000032742	ENSSSCP00000003758	Uncharacterized protein.	Caspase 9; Belongs to the peptidase C14A family.	0.700
BAK1	DIABLO	ENSSSCP00000032742	ENSSSCP00000010461	Uncharacterized protein.	Uncharacterized protein.	0.824
BAK1	XIAP	ENSSSCP00000032742	ENSSSCP00000039589	Uncharacterized protein.	X-linked inhibitor of apoptosis.	0.521
BIRC3	BIRC5	ENSSSCP00000049500	ENSSSCP00000042198	Baculoviral IAP repeat containing 3.	Baculoviral IAP repeat-containing protein 5; Multitasking protein that has dual roles in promoting cell proliferation and preventing apoptosis (By similarity). Component of a chromosome passage protein complex (CPC) which is essential for chromosome alignment and segregation during mitosis and cytokinesis (By similarity). Acts as an important regulator of the localization of this complex; directs CPC movement to different locations from the inner centromere during prometaphase to midbody during cytokinesis and participates in the organization of the center spindle by associating with p [...]	0.969
BIRC3	BIRC7	ENSSSCP00000049500	ENSSSCP00000055714	Baculoviral IAP repeat containing 3.	RING-type domain-containing protein.	0.890
BIRC3	BIRC7-2	ENSSSCP00000049500	ENSSSCP00000073011	Baculoviral IAP repeat containing 3.	Uncharacterized protein.	0.890
BIRC3	CASP7	ENSSSCP00000049500	ENSSSCP00000043126	Baculoviral IAP repeat containing 3.	Caspase 7; Belongs to the peptidase C14A family.	0.986
BIRC3	CASP9	ENSSSCP00000049500	ENSSSCP00000003758	Baculoviral IAP repeat containing 3.	Caspase 9; Belongs to the peptidase C14A family.	0.988
BIRC3	DIABLO	ENSSSCP00000049500	ENSSSCP00000010461	Baculoviral IAP repeat containing 3.	Uncharacterized protein.	0.982
BIRC3	HTRA2	ENSSSCP00000049500	ENSSSCP00000039563	Baculoviral IAP repeat containing 3.	HtrA serine peptidase 2.	0.984
BIRC3	XIAP	ENSSSCP00000049500	ENSSSCP00000039589	Baculoviral IAP repeat containing 3.	X-linked inhibitor of apoptosis.	0.996
BIRC5	BIRC3	ENSSSCP00000042198	ENSSSCP00000049500	Baculoviral IAP repeat-containing protein 5; Multitasking protein that has dual roles in promoting cell proliferation and preventing apoptosis (By similarity). Component of a chromosome passage protein complex (CPC) which is essential for chromosome alignment and segregation during mitosis and cytokinesis (By similarity). Acts as an important regulator of the localization of this complex; directs CPC movement to different locations from the inner centromere during prometaphase to midbody during cytokinesis and participates in the organization of the center spindle by associating with p [...]	Baculoviral IAP repeat containing 3.	0.969
BIRC5	BIRC6	ENSSSCP00000042198	ENSSSCP00000009078	Baculoviral IAP repeat-containing protein 5; Multitasking protein that has dual roles in promoting cell proliferation and preventing apoptosis (By similarity). Component of a chromosome passage protein complex (CPC) which is essential for chromosome alignment and segregation during mitosis and cytokinesis (By similarity). Acts as an important regulator of the localization of this complex; directs CPC movement to different locations from the inner centromere during prometaphase to midbody during cytokinesis and participates in the organization of the center spindle by associating with p [...]	Baculoviral IAP repeat containing 6.	0.900
BIRC5	BIRC7	ENSSSCP00000042198	ENSSSCP00000055714	Baculoviral IAP repeat-containing protein 5; Multitasking protein that has dual roles in promoting cell proliferation and preventing apoptosis (By similarity). Component of a chromosome passage protein complex (CPC) which is essential for chromosome alignment and segregation during mitosis and cytokinesis (By similarity). Acts as an important regulator of the localization of this complex; directs CPC movement to different locations from the inner centromere during prometaphase to midbody during cytokinesis and participates in the organization of the center spindle by associating with p [...]	RING-type domain-containing protein.	0.853
BIRC5	BIRC7-2	ENSSSCP00000042198	ENSSSCP00000073011	Baculoviral IAP repeat-containing protein 5; Multitasking protein that has dual roles in promoting cell proliferation and preventing apoptosis (By similarity). Component of a chromosome passage protein complex (CPC) which is essential for chromosome alignment and segregation during mitosis and cytokinesis (By similarity). Acts as an important regulator of the localization of this complex; directs CPC movement to different locations from the inner centromere during prometaphase to midbody during cytokinesis and participates in the organization of the center spindle by associating with p [...]	Uncharacterized protein.	0.793
BIRC5	CASP7	ENSSSCP00000042198	ENSSSCP00000043126	Baculoviral IAP repeat-containing protein 5; Multitasking protein that has dual roles in promoting cell proliferation and preventing apoptosis (By similarity). Component of a chromosome passage protein complex (CPC) which is essential for chromosome alignment and segregation during mitosis and cytokinesis (By similarity). Acts as an important regulator of the localization of this complex; directs CPC movement to different locations from the inner centromere during prometaphase to midbody during cytokinesis and participates in the organization of the center spindle by associating with p [...]	Caspase 7; Belongs to the peptidase C14A family.	0.973
BIRC5	CASP9	ENSSSCP00000042198	ENSSSCP00000003758	Baculoviral IAP repeat-containing protein 5; Multitasking protein that has dual roles in promoting cell proliferation and preventing apoptosis (By similarity). Component of a chromosome passage protein complex (CPC) which is essential for chromosome alignment and segregation during mitosis and cytokinesis (By similarity). Acts as an important regulator of the localization of this complex; directs CPC movement to different locations from the inner centromere during prometaphase to midbody during cytokinesis and participates in the organization of the center spindle by associating with p [...]	Caspase 9; Belongs to the peptidase C14A family.	0.987
BIRC5	DIABLO	ENSSSCP00000042198	ENSSSCP00000010461	Baculoviral IAP repeat-containing protein 5; Multitasking protein that has dual roles in promoting cell proliferation and preventing apoptosis (By similarity). Component of a chromosome passage protein complex (CPC) which is essential for chromosome alignment and segregation during mitosis and cytokinesis (By similarity). Acts as an important regulator of the localization of this complex; directs CPC movement to different locations from the inner centromere during prometaphase to midbody during cytokinesis and participates in the organization of the center spindle by associating with p [...]	Uncharacterized protein.	0.980
BIRC5	HTRA2	ENSSSCP00000042198	ENSSSCP00000039563	Baculoviral IAP repeat-containing protein 5; Multitasking protein that has dual roles in promoting cell proliferation and preventing apoptosis (By similarity). Component of a chromosome passage protein complex (CPC) which is essential for chromosome alignment and segregation during mitosis and cytokinesis (By similarity). Acts as an important regulator of the localization of this complex; directs CPC movement to different locations from the inner centromere during prometaphase to midbody during cytokinesis and participates in the organization of the center spindle by associating with p [...]	HtrA serine peptidase 2.	0.910