DIABLO protein (Sus scrofa) - STRING interaction network

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

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second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

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[Homology]

Score

DIABLO

Uncharacterized protein. (237 aa)

Predicted Functional Partners:

XIAP

0.989

BIRC5

0.976

BIRC3

0.970

BIRC6

0.966

CASP7

0.826

BAK1

0.801

APAF1

0.778

HTRA2

0.740

CYCS

0.699

CASP9

0.690

Your Current Organism:

Sus scrofa

NCBI taxonomy Id: 9823
Other names: S. scrofa, pig, pigs, swine, wild boar

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
APAF1	BAK1	ENSSSCP00000042119	ENSSSCP00000032742	Apoptotic protease-activating factor 1; Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP.	Uncharacterized protein.	0.779
APAF1	BIRC3	ENSSSCP00000042119	ENSSSCP00000049500	Apoptotic protease-activating factor 1; Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP.	Baculoviral IAP repeat containing 3.	0.467
APAF1	BIRC5	ENSSSCP00000042119	ENSSSCP00000042198	Apoptotic protease-activating factor 1; Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP.	Baculoviral IAP repeat-containing protein 5; Multitasking protein that has dual roles in promoting cell proliferation and preventing apoptosis (By similarity). Component of a chromosome passage protein complex (CPC) which is essential for chromosome alignment and segregation during mitosis and cytokinesis (By similarity). Acts as an important regulator of the localization of this complex; directs CPC movement to different locations from the inner centromere during prometaphase to midbody during cytokinesis and participates in the organization of the center spindle by associating with p [...]	0.442
APAF1	BIRC6	ENSSSCP00000042119	ENSSSCP00000009078	Apoptotic protease-activating factor 1; Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP.	Baculoviral IAP repeat containing 6.	0.587
APAF1	CASP7	ENSSSCP00000042119	ENSSSCP00000043126	Apoptotic protease-activating factor 1; Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP.	Caspase 7; Belongs to the peptidase C14A family.	0.921
APAF1	CASP9	ENSSSCP00000042119	ENSSSCP00000003758	Apoptotic protease-activating factor 1; Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP.	Caspase 9; Belongs to the peptidase C14A family.	0.999
APAF1	CYCS	ENSSSCP00000042119	ENSSSCP00000017704	Apoptotic protease-activating factor 1; Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP.	Cytochrome c; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain.	0.999
APAF1	DIABLO	ENSSSCP00000042119	ENSSSCP00000010461	Apoptotic protease-activating factor 1; Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP.	Uncharacterized protein.	0.778
APAF1	HTRA2	ENSSSCP00000042119	ENSSSCP00000039563	Apoptotic protease-activating factor 1; Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP.	HtrA serine peptidase 2.	0.646
APAF1	XIAP	ENSSSCP00000042119	ENSSSCP00000039589	Apoptotic protease-activating factor 1; Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP.	X-linked inhibitor of apoptosis.	0.893
BAK1	APAF1	ENSSSCP00000032742	ENSSSCP00000042119	Uncharacterized protein.	Apoptotic protease-activating factor 1; Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP.	0.779
BAK1	CASP7	ENSSSCP00000032742	ENSSSCP00000043126	Uncharacterized protein.	Caspase 7; Belongs to the peptidase C14A family.	0.535
BAK1	CASP9	ENSSSCP00000032742	ENSSSCP00000003758	Uncharacterized protein.	Caspase 9; Belongs to the peptidase C14A family.	0.630
BAK1	CYCS	ENSSSCP00000032742	ENSSSCP00000017704	Uncharacterized protein.	Cytochrome c; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain.	0.945
BAK1	DIABLO	ENSSSCP00000032742	ENSSSCP00000010461	Uncharacterized protein.	Uncharacterized protein.	0.801
BIRC3	APAF1	ENSSSCP00000049500	ENSSSCP00000042119	Baculoviral IAP repeat containing 3.	Apoptotic protease-activating factor 1; Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP.	0.467
BIRC3	BIRC5	ENSSSCP00000049500	ENSSSCP00000042198	Baculoviral IAP repeat containing 3.	Baculoviral IAP repeat-containing protein 5; Multitasking protein that has dual roles in promoting cell proliferation and preventing apoptosis (By similarity). Component of a chromosome passage protein complex (CPC) which is essential for chromosome alignment and segregation during mitosis and cytokinesis (By similarity). Acts as an important regulator of the localization of this complex; directs CPC movement to different locations from the inner centromere during prometaphase to midbody during cytokinesis and participates in the organization of the center spindle by associating with p [...]	0.938
BIRC3	CASP7	ENSSSCP00000049500	ENSSSCP00000043126	Baculoviral IAP repeat containing 3.	Caspase 7; Belongs to the peptidase C14A family.	0.962
BIRC3	CASP9	ENSSSCP00000049500	ENSSSCP00000003758	Baculoviral IAP repeat containing 3.	Caspase 9; Belongs to the peptidase C14A family.	0.972
BIRC3	DIABLO	ENSSSCP00000049500	ENSSSCP00000010461	Baculoviral IAP repeat containing 3.	Uncharacterized protein.	0.970