STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TAOK3TAO kinase 3. (898 aa)    
Predicted Functional Partners:
MAP2K6
Mitogen-activated protein kinase kinase 6; Belongs to the protein kinase superfamily.
    
0.914
TAOK1
Serine/threonine-protein kinase TAO1 isoform 1.
  
 
0.908
YBX3
Y-box binding protein 3.
      
 0.609
PHRF1
PHD and ring finger domains 1.
   
  
 0.605
APIP
Methylthioribulose-1-phosphate dehydratase; Catalyzes the dehydration of methylthioribulose-1-phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P). Functions in the methionine salvage pathway, which plays a key role in cancer, apoptosis, microbial proliferation and inflammation. May inhibit the CASP1-related inflammatory response (pyroptosis), the CASP9-dependent apoptotic pathway and the cytochrome c-dependent and APAF1-mediated cell death; Belongs to the aldolase class II family. MtnB subfamily.
      
 0.579
ING2
Inhibitor of growth protein.
   
  
 0.551
SPPL3
Signal peptide peptidase like 3.
      
 0.516
RAC3
Rac family small GTPase 3.
    
  0.516
RAC1
Rac family small GTPase 1.
    
  0.516
RAC2
Rac family small GTPase 2.
    
  0.516
Your Current Organism:
Sus scrofa
NCBI taxonomy Id: 9823
Other names: S. scrofa, pig, pigs, swine, wild boar
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.