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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
RASAL1RAS protein activator like 1. (784 aa)    
Predicted Functional Partners:
NRAS
GTPase NRas; Ras proteins bind GDP/GTP and possess intrinsic GTPase activity; Belongs to the small GTPase superfamily. Ras family.
    
 0.572
MCF2L
MCF.2 cell line derived transforming sequence like.
      
 0.570
KRAS
KRAS proto-oncogene, GTPase.
    
 0.563
HRAS
HRas proto-oncogene, GTPase.
    
 0.563
NF1
Neurofibromin 1.
   
 
0.560
IL1RAPL1
Interleukin 1 receptor accessory protein like 1.
      
 0.550
PTPN3
Tyrosine-protein phosphatase non-receptor type; May act at junctions between the membrane and the cytoskeleton.
    
 
 0.548
LAX1
Lymphocyte transmembrane adaptor 1.
      
 0.538
RASAL2
RAS protein activator like 2.
    
0.534
GAPVD1
GTPase activating protein and VPS9 domains 1.
    
 
 0.530
Your Current Organism:
Sus scrofa
NCBI taxonomy Id: 9823
Other names: S. scrofa, pig, pigs, swine, wild boar
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.