close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING newly available directed regulatory networks a new typed view showing functional, physical, and regulatory edges in one network new clustering options and cluster-based layouts … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
FAM222AFamily with sequence similarity 222 member A. (454 aa)    
Predicted Functional Partners:
SCYL1
SCY1 like pseudokinase 1.
      
 0.659
F1RKR0_PIG
Uncharacterized protein.
      
 0.514
C7orf57
Chromosome 7 open reading frame 57.
      
 0.514
MTF1
Metal regulatory transcription factor 1.
      
 0.503
DUSP15
Dual specificity phosphatase 15; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily.
      
 0.499
GABPB1
GA binding protein transcription factor subunit beta 1.
      
 0.499
TOMM40
Translocase of outer mitochondrial membrane 40.
      
 0.485
PCDH18
Protocadherin 18.
      
 0.465
CDH18
Cadherin 18; Cadherins are calcium-dependent cell adhesion proteins.
      
 0.463
GUCA1B
Guanylate cyclase activator 1B.
      
 0.451
Your Current Organism:
Sus scrofa
NCBI taxonomy Id: 9823
Other names: S. scrofa, pig, pigs, swine, wild boar
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