Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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experimentally determined
co-expression
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gene co-occurrence
gene fusions
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[Homology]
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DAOD-amino-acid oxidase; Regulates the level of the neuromodulator D-serine in the brain. Has high activity towards D-DOPA and contributes to dopamine synthesis. Could act as a detoxifying agent which removes D-amino acids accumulated during aging. Acts on a variety of D-amino acids with a preference for those having small hydrophobic side chains followed by those bearing polar, aromatic, and basic groups. Does not act on acidic amino acids. (371 aa)    
Predicted Functional Partners:
HAO1
Hydroxyacid oxidase 1.
   
 
 0.981
AGXT
Serine--pyruvate aminotransferase.
  
 
 0.974
HAO2
Hydroxyacid oxidase 2 isoform 1.
   
 
 0.971
GLDC
Glycine cleavage system P protein; The glycine cleavage system catalyzes the degradation of glycine.
   
 
 0.959
SARDH
Sarcosine dehydrogenase, mitochondrial.
  
 0.943
AGXT2
Uncharacterized protein; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
  
 
 0.941
SHMT1
Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family.
  
 
 0.937
PIPOX
Pipecolic acid and sarcosine oxidase.
   
 
 0.937
SHMT2
Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family.
  
 
 0.937
L3HYPDH
Trans-3-hydroxy-L-proline dehydratase isoform a.
  
 
 0.934
Your Current Organism:
Sus scrofa
NCBI taxonomy Id: 9823
Other names: S. scrofa, pig, pigs, swine, wild boar
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