Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
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Experiments
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[Homology]
Score
TBC1D10ATBC1 domain family member 10A isoform 2. (545 aa)    
Predicted Functional Partners:
SYTL1
Synaptotagmin like 1.
     
 0.906
RAB35
Uncharacterized protein.
   
 0.870
SLC9A3R1
Na(+)/H(+) exchange regulatory cofactor NHE-RF; Scaffold protein that connects plasma membrane proteins with members of the ezrin/moesin/radixin family and thereby helps to link them to the actin cytoskeleton and to regulate their surface expression.
    
 
 0.854
ARF6
ADP-ribosylation factor 6; GTP-binding protein involved in protein trafficking that regulates endocytic recycling and cytoskeleton remodeling (By similarity). Required for normal completion of mitotic cytokinesis (By similarity). Plays a role in the reorganization of the actin cytoskeleton and the formation of stress fibers (By similarity). Involved in the regulation of dendritic spine development, contributing to the regulation of dendritic branching and filopodia extension (By similarity). Plays an important role in membrane trafficking, during junctional remodeling and epithelial po [...]
   
 
 0.743
TBC1D21
TBC1 domain family member 21.
   
  
 0.723
TBC1D22B
TBC1 domain family member 22B.
      
 0.722
TBC1D13
TBC1 domain family member 13.
      
 0.720
IFT81
Intraflagellar transport 81.
      
 0.693
EZR
Ezrin.
    
 
 0.686
SLC9A3R2
SLC9A3 regulator 2.
    
 
 0.652
Your Current Organism:
Sus scrofa
NCBI taxonomy Id: 9823
Other names: S. scrofa, pig, pigs, swine, wild boar
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