Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
OSBP2Oxysterol-binding protein; Belongs to the OSBP family. (1042 aa)    
Predicted Functional Partners:
VAPB
Vesicle-associated membrane protein-associated protein B; Participates in the endoplasmic reticulum unfolded protein response (UPR) by inducing ERN1/IRE1 activity. Involved in cellular calcium homeostasis regulation.
    
 
 0.876
VAPA
VAMP associated protein A.
    
 
 0.864
OSBP
Oxysterol-binding protein; Belongs to the OSBP family.
    
   0.796
ZNF22
Zinc finger protein 22.
      
 0.741
EIF4ENIF1
Eukaryotic translation initiation factor 4E nuclear import factor 1.
    
 
 0.708
MORC2
MORC family CW-type zinc finger protein 2 isoform X2.
      
 0.626
ATP8B4
Phospholipid-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily.
    
 
 0.621
LZTS1
Leucine zipper putative tumor suppressor 1 isoform X1.
      
 0.616
LIMK2
LIM domain kinase 2.
    
 
 0.599
GAL3ST4
Galactose-3-O-sulfotransferase 4.
      
 0.597
Your Current Organism:
Sus scrofa
NCBI taxonomy Id: 9823
Other names: S. scrofa, pig, pigs, swine, wild boar
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