STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PIK3IP1Phosphoinositide-3-kinase interacting protein 1. (296 aa)    
Predicted Functional Partners:
PIP4K2B
Phosphatidylinositol 5-phosphate 4-kinase type-2 beta.
      
 0.673
PIP4K2A
Phosphatidylinositol 5-phosphate 4-kinase type-2 alpha; Catalyzes the phosphorylation of phosphatidylinositol 5- phosphate (PtdIns5P) on the fourth hydroxyl of the myo-inositol ring, to form phosphatidylinositol 4,5-bisphosphate (PtdIns(4,5)P2). May exert its function by regulating the levels of PtdIns5P, which functions in the cytosol by increasing AKT activity and in the nucleus signals through ING2. May regulate the pool of cytosolic PtdIns5P in response to the activation of tyrosine phosphorylation. May negatively regulate insulin-stimulated glucose uptake by lowering the levels of [...]
      
 0.664
PIP4K2C
Phosphatidylinositol-5-phosphate 4-kinase type 2 gamma.
      
 0.655
LRRC14
Leucine-rich repeat-containing protein 14 isoform X1.
      
 0.653
LRRC14B
Leucine-rich repeat-containing protein 14B.
      
 0.651
TAF3
TATA-box binding protein associated factor 3.
      
 0.635
PDXK
Pyridoxal kinase; Required for synthesis of pyridoxal-5-phosphate from vitamin B6; Belongs to the pyridoxine kinase family.
      
 0.574
ING2
Inhibitor of growth protein.
      
 0.568
ADGRE5
Adhesion G protein-coupled receptor E5; Belongs to the G-protein coupled receptor 2 family.
      
 0.541
SDR9C7
Short chain dehydrogenase/reductase family 9C member 7; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
      
 0.536
Your Current Organism:
Sus scrofa
NCBI taxonomy Id: 9823
Other names: S. scrofa, pig, pigs, swine, wild boar
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