Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
PPM1FProtein phosphatase, Mg2+/Mn2+ dependent 1F. (436 aa)    
Predicted Functional Partners:
TANGO2
Transport and golgi organization 2 homolog.
      
 0.864
GSC2
Goosecoid homeobox 2.
    
 
 0.743
WSCD2
WSC domain containing 2.
   
 
 0.732
GALNT9
Polypeptide N-acetylgalactosaminyltransferase.
      
 0.696
CCDC92
Coiled-coil domain-containing protein 92 isoform X1.
      
 0.687
BABAM1
BRISC and BRCA1 A complex member 1.
      
 0.685
ANAPC7
Anaphase promoting complex subunit 7.
      
 0.680
TOP3B
DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family.
   
  
 0.672
ESS2
Ess-2 splicing factor homolog.
   
  
 0.672
TSSK2
Testis-specific serine kinase 2; Belongs to the protein kinase superfamily.
   
 0.670
Your Current Organism:
Sus scrofa
NCBI taxonomy Id: 9823
Other names: S. scrofa, pig, pigs, swine, wild boar
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