STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CRKLCRK like proto-oncogene, adaptor protein. (303 aa)    
Predicted Functional Partners:
CBL
Cbl proto-oncogene.
    
 0.995
RAPGEF1
Rap guanine nucleotide exchange factor 1.
    
 0.988
GAB1
GRB2 associated binding protein 1.
    
 0.977
EGFR
Receptor protein-tyrosine kinase.
    
 0.969
BCAR1
BCAR1 scaffold protein, Cas family member.
    
 0.967
PXN
Uncharacterized protein.
    
 0.963
SRC
Tyrosine-protein kinase.
   
0.959
ABL1
Tyrosine-protein kinase.
    
0.959
ELMO2
Engulfment and cell motility 2.
    
 0.938
FRS2
Fibroblast growth factor receptor substrate 2.
   
 0.935
Your Current Organism:
Sus scrofa
NCBI taxonomy Id: 9823
Other names: S. scrofa, pig, pigs, swine, wild boar
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.