node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
PREB | SAR1A | ENSSSCP00000009118 | ENSSSCP00000039382 | Prolactin regulatory element binding. | GTP-binding protein SAR1a; Involved in transport from the endoplasmic reticulum to the Golgi apparatus. Required to maintain SEC16A localization at discrete locations on the ER membrane perhaps by preventing its dissociation. SAR1A-GTP-dependent assembly of SEC16A on the ER membrane forms an organized scaffold defining endoplasmic reticulum exit sites (ERES) (By similarity). | 0.975 |
PREB | SAR1B | ENSSSCP00000009118 | ENSSSCP00000042292 | Prolactin regulatory element binding. | GTP-binding protein SAR1b; Involved in transport from the endoplasmic reticulum to the Golgi apparatus. Activated by the guanine nucleotide exchange factor PREB. Involved in the selection of the protein cargo and the assembly of the COPII coat complex (By similarity). | 0.975 |
PREB | SEC13 | ENSSSCP00000009118 | ENSSSCP00000073167 | Prolactin regulatory element binding. | SEC13 homolog, nuclear pore and COPII coat complex component; Belongs to the WD repeat SEC13 family. | 0.530 |
PREB | SEC23A | ENSSSCP00000009118 | ENSSSCP00000002115 | Prolactin regulatory element binding. | Protein transport protein SEC23; Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules; Belongs to the SEC23/SEC24 family. SEC23 subfamily. | 0.724 |
PREB | SEC23B | ENSSSCP00000009118 | ENSSSCP00000047966 | Prolactin regulatory element binding. | Protein transport protein SEC23; Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules; Belongs to the SEC23/SEC24 family. SEC23 subfamily. | 0.471 |
PREB | SEC24A | ENSSSCP00000009118 | ENSSSCP00000048484 | Prolactin regulatory element binding. | SEC24 homolog A, COPII coat complex component. | 0.698 |
PREB | SEC24B | ENSSSCP00000009118 | ENSSSCP00000009748 | Prolactin regulatory element binding. | SEC24 homolog B, COPII coat complex component. | 0.763 |
PREB | SEC24C | ENSSSCP00000009118 | ENSSSCP00000010987 | Prolactin regulatory element binding. | SEC24 homolog C, COPII coat complex component. | 0.751 |
PREB | SEC31A | ENSSSCP00000009118 | ENSSSCP00000067869 | Prolactin regulatory element binding. | SEC31 homolog A, COPII coat complex component. | 0.415 |
PREB | SEC31B | ENSSSCP00000009118 | ENSSSCP00000072215 | Prolactin regulatory element binding. | SEC31 homolog B, COPII coat complex component. | 0.415 |
SAR1A | PREB | ENSSSCP00000039382 | ENSSSCP00000009118 | GTP-binding protein SAR1a; Involved in transport from the endoplasmic reticulum to the Golgi apparatus. Required to maintain SEC16A localization at discrete locations on the ER membrane perhaps by preventing its dissociation. SAR1A-GTP-dependent assembly of SEC16A on the ER membrane forms an organized scaffold defining endoplasmic reticulum exit sites (ERES) (By similarity). | Prolactin regulatory element binding. | 0.975 |
SAR1A | SAR1B | ENSSSCP00000039382 | ENSSSCP00000042292 | GTP-binding protein SAR1a; Involved in transport from the endoplasmic reticulum to the Golgi apparatus. Required to maintain SEC16A localization at discrete locations on the ER membrane perhaps by preventing its dissociation. SAR1A-GTP-dependent assembly of SEC16A on the ER membrane forms an organized scaffold defining endoplasmic reticulum exit sites (ERES) (By similarity). | GTP-binding protein SAR1b; Involved in transport from the endoplasmic reticulum to the Golgi apparatus. Activated by the guanine nucleotide exchange factor PREB. Involved in the selection of the protein cargo and the assembly of the COPII coat complex (By similarity). | 0.903 |
SAR1A | SEC13 | ENSSSCP00000039382 | ENSSSCP00000073167 | GTP-binding protein SAR1a; Involved in transport from the endoplasmic reticulum to the Golgi apparatus. Required to maintain SEC16A localization at discrete locations on the ER membrane perhaps by preventing its dissociation. SAR1A-GTP-dependent assembly of SEC16A on the ER membrane forms an organized scaffold defining endoplasmic reticulum exit sites (ERES) (By similarity). | SEC13 homolog, nuclear pore and COPII coat complex component; Belongs to the WD repeat SEC13 family. | 0.970 |
SAR1A | SEC23A | ENSSSCP00000039382 | ENSSSCP00000002115 | GTP-binding protein SAR1a; Involved in transport from the endoplasmic reticulum to the Golgi apparatus. Required to maintain SEC16A localization at discrete locations on the ER membrane perhaps by preventing its dissociation. SAR1A-GTP-dependent assembly of SEC16A on the ER membrane forms an organized scaffold defining endoplasmic reticulum exit sites (ERES) (By similarity). | Protein transport protein SEC23; Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules; Belongs to the SEC23/SEC24 family. SEC23 subfamily. | 0.901 |
SAR1A | SEC23B | ENSSSCP00000039382 | ENSSSCP00000047966 | GTP-binding protein SAR1a; Involved in transport from the endoplasmic reticulum to the Golgi apparatus. Required to maintain SEC16A localization at discrete locations on the ER membrane perhaps by preventing its dissociation. SAR1A-GTP-dependent assembly of SEC16A on the ER membrane forms an organized scaffold defining endoplasmic reticulum exit sites (ERES) (By similarity). | Protein transport protein SEC23; Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules; Belongs to the SEC23/SEC24 family. SEC23 subfamily. | 0.900 |
SAR1A | SEC24A | ENSSSCP00000039382 | ENSSSCP00000048484 | GTP-binding protein SAR1a; Involved in transport from the endoplasmic reticulum to the Golgi apparatus. Required to maintain SEC16A localization at discrete locations on the ER membrane perhaps by preventing its dissociation. SAR1A-GTP-dependent assembly of SEC16A on the ER membrane forms an organized scaffold defining endoplasmic reticulum exit sites (ERES) (By similarity). | SEC24 homolog A, COPII coat complex component. | 0.888 |
SAR1A | SEC24B | ENSSSCP00000039382 | ENSSSCP00000009748 | GTP-binding protein SAR1a; Involved in transport from the endoplasmic reticulum to the Golgi apparatus. Required to maintain SEC16A localization at discrete locations on the ER membrane perhaps by preventing its dissociation. SAR1A-GTP-dependent assembly of SEC16A on the ER membrane forms an organized scaffold defining endoplasmic reticulum exit sites (ERES) (By similarity). | SEC24 homolog B, COPII coat complex component. | 0.852 |
SAR1A | SEC24C | ENSSSCP00000039382 | ENSSSCP00000010987 | GTP-binding protein SAR1a; Involved in transport from the endoplasmic reticulum to the Golgi apparatus. Required to maintain SEC16A localization at discrete locations on the ER membrane perhaps by preventing its dissociation. SAR1A-GTP-dependent assembly of SEC16A on the ER membrane forms an organized scaffold defining endoplasmic reticulum exit sites (ERES) (By similarity). | SEC24 homolog C, COPII coat complex component. | 0.833 |
SAR1A | SEC31A | ENSSSCP00000039382 | ENSSSCP00000067869 | GTP-binding protein SAR1a; Involved in transport from the endoplasmic reticulum to the Golgi apparatus. Required to maintain SEC16A localization at discrete locations on the ER membrane perhaps by preventing its dissociation. SAR1A-GTP-dependent assembly of SEC16A on the ER membrane forms an organized scaffold defining endoplasmic reticulum exit sites (ERES) (By similarity). | SEC31 homolog A, COPII coat complex component. | 0.968 |
SAR1A | SEC31B | ENSSSCP00000039382 | ENSSSCP00000072215 | GTP-binding protein SAR1a; Involved in transport from the endoplasmic reticulum to the Golgi apparatus. Required to maintain SEC16A localization at discrete locations on the ER membrane perhaps by preventing its dissociation. SAR1A-GTP-dependent assembly of SEC16A on the ER membrane forms an organized scaffold defining endoplasmic reticulum exit sites (ERES) (By similarity). | SEC31 homolog B, COPII coat complex component. | 0.968 |