node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
CDH10 | KCNMA1 | ENSSSCP00000017797 | ENSSSCP00000032909 | Cadherin-10 isoform X1; Cadherins are calcium-dependent cell adhesion proteins. | Calcium-activated potassium channel subunit alpha-1; Potassium channel activated by both membrane depolarization or increase in cytosolic Ca(2+) that mediates export of K(+). It is also activated by the concentration of cytosolic Mg(2+). Its activation dampens the excitatory events that elevate the cytosolic Ca(2+) concentration and/or depolarize the cell membrane. It therefore contributes to repolarization of the membrane potential. Plays a key role in controlling excitability in a number of systems, such as regulation of the contraction of smooth muscle, the tuning of hair cells in t [...] | 0.603 |
CDH10 | TBCB | ENSSSCP00000017797 | ENSSSCP00000003151 | Cadherin-10 isoform X1; Cadherins are calcium-dependent cell adhesion proteins. | Cytoskeleton-associated protein 1. | 0.723 |
CHRNA4 | KCNMA1 | ENSSSCP00000032042 | ENSSSCP00000032909 | Cholinergic receptor nicotinic alpha 4 subunit. | Calcium-activated potassium channel subunit alpha-1; Potassium channel activated by both membrane depolarization or increase in cytosolic Ca(2+) that mediates export of K(+). It is also activated by the concentration of cytosolic Mg(2+). Its activation dampens the excitatory events that elevate the cytosolic Ca(2+) concentration and/or depolarize the cell membrane. It therefore contributes to repolarization of the membrane potential. Plays a key role in controlling excitability in a number of systems, such as regulation of the contraction of smooth muscle, the tuning of hair cells in t [...] | 0.584 |
KCNMA1 | CDH10 | ENSSSCP00000032909 | ENSSSCP00000017797 | Calcium-activated potassium channel subunit alpha-1; Potassium channel activated by both membrane depolarization or increase in cytosolic Ca(2+) that mediates export of K(+). It is also activated by the concentration of cytosolic Mg(2+). Its activation dampens the excitatory events that elevate the cytosolic Ca(2+) concentration and/or depolarize the cell membrane. It therefore contributes to repolarization of the membrane potential. Plays a key role in controlling excitability in a number of systems, such as regulation of the contraction of smooth muscle, the tuning of hair cells in t [...] | Cadherin-10 isoform X1; Cadherins are calcium-dependent cell adhesion proteins. | 0.603 |
KCNMA1 | CHRNA4 | ENSSSCP00000032909 | ENSSSCP00000032042 | Calcium-activated potassium channel subunit alpha-1; Potassium channel activated by both membrane depolarization or increase in cytosolic Ca(2+) that mediates export of K(+). It is also activated by the concentration of cytosolic Mg(2+). Its activation dampens the excitatory events that elevate the cytosolic Ca(2+) concentration and/or depolarize the cell membrane. It therefore contributes to repolarization of the membrane potential. Plays a key role in controlling excitability in a number of systems, such as regulation of the contraction of smooth muscle, the tuning of hair cells in t [...] | Cholinergic receptor nicotinic alpha 4 subunit. | 0.584 |
KCNMA1 | KCNMB1 | ENSSSCP00000032909 | ENSSSCP00000018017 | Calcium-activated potassium channel subunit alpha-1; Potassium channel activated by both membrane depolarization or increase in cytosolic Ca(2+) that mediates export of K(+). It is also activated by the concentration of cytosolic Mg(2+). Its activation dampens the excitatory events that elevate the cytosolic Ca(2+) concentration and/or depolarize the cell membrane. It therefore contributes to repolarization of the membrane potential. Plays a key role in controlling excitability in a number of systems, such as regulation of the contraction of smooth muscle, the tuning of hair cells in t [...] | Potassium calcium-activated channel subfamily M regulatory beta subunit 1. | 0.807 |
KCNMA1 | KCNMB3 | ENSSSCP00000032909 | ENSSSCP00000027661 | Calcium-activated potassium channel subunit alpha-1; Potassium channel activated by both membrane depolarization or increase in cytosolic Ca(2+) that mediates export of K(+). It is also activated by the concentration of cytosolic Mg(2+). Its activation dampens the excitatory events that elevate the cytosolic Ca(2+) concentration and/or depolarize the cell membrane. It therefore contributes to repolarization of the membrane potential. Plays a key role in controlling excitability in a number of systems, such as regulation of the contraction of smooth muscle, the tuning of hair cells in t [...] | Potassium calcium-activated channel subfamily M regulatory beta subunit 3; Belongs to the class-I aminoacyl-tRNA synthetase family. | 0.583 |
KCNMA1 | KCNMB4 | ENSSSCP00000032909 | ENSSSCP00000045790 | Calcium-activated potassium channel subunit alpha-1; Potassium channel activated by both membrane depolarization or increase in cytosolic Ca(2+) that mediates export of K(+). It is also activated by the concentration of cytosolic Mg(2+). Its activation dampens the excitatory events that elevate the cytosolic Ca(2+) concentration and/or depolarize the cell membrane. It therefore contributes to repolarization of the membrane potential. Plays a key role in controlling excitability in a number of systems, such as regulation of the contraction of smooth muscle, the tuning of hair cells in t [...] | Potassium calcium-activated channel subfamily M regulatory beta subunit 4. | 0.985 |
KCNMA1 | KCNN3 | ENSSSCP00000032909 | ENSSSCP00000006973 | Calcium-activated potassium channel subunit alpha-1; Potassium channel activated by both membrane depolarization or increase in cytosolic Ca(2+) that mediates export of K(+). It is also activated by the concentration of cytosolic Mg(2+). Its activation dampens the excitatory events that elevate the cytosolic Ca(2+) concentration and/or depolarize the cell membrane. It therefore contributes to repolarization of the membrane potential. Plays a key role in controlling excitability in a number of systems, such as regulation of the contraction of smooth muscle, the tuning of hair cells in t [...] | Small conductance calcium-activated potassium channel protein 3; Forms a voltage-independent potassium channel activated by intracellular calcium. Activation is followed by membrane hyperpolarization. Thought to regulate neuronal excitability by contributing to the slow component of synaptic afterhyperpolarization. The channel is blocked by apamin (By similarity). | 0.652 |
KCNMA1 | KCNN4 | ENSSSCP00000032909 | ENSSSCP00000003323 | Calcium-activated potassium channel subunit alpha-1; Potassium channel activated by both membrane depolarization or increase in cytosolic Ca(2+) that mediates export of K(+). It is also activated by the concentration of cytosolic Mg(2+). Its activation dampens the excitatory events that elevate the cytosolic Ca(2+) concentration and/or depolarize the cell membrane. It therefore contributes to repolarization of the membrane potential. Plays a key role in controlling excitability in a number of systems, such as regulation of the contraction of smooth muscle, the tuning of hair cells in t [...] | Intermediate conductance calcium-activated potassium channel protein 4. | 0.826 |
KCNMA1 | KCNQ4 | ENSSSCP00000032909 | ENSSSCP00000004297 | Calcium-activated potassium channel subunit alpha-1; Potassium channel activated by both membrane depolarization or increase in cytosolic Ca(2+) that mediates export of K(+). It is also activated by the concentration of cytosolic Mg(2+). Its activation dampens the excitatory events that elevate the cytosolic Ca(2+) concentration and/or depolarize the cell membrane. It therefore contributes to repolarization of the membrane potential. Plays a key role in controlling excitability in a number of systems, such as regulation of the contraction of smooth muscle, the tuning of hair cells in t [...] | Potassium voltage-gated channel subfamily Q member 4; Belongs to the potassium channel family. | 0.592 |
KCNMA1 | LRRC26 | ENSSSCP00000032909 | ENSSSCP00000056401 | Calcium-activated potassium channel subunit alpha-1; Potassium channel activated by both membrane depolarization or increase in cytosolic Ca(2+) that mediates export of K(+). It is also activated by the concentration of cytosolic Mg(2+). Its activation dampens the excitatory events that elevate the cytosolic Ca(2+) concentration and/or depolarize the cell membrane. It therefore contributes to repolarization of the membrane potential. Plays a key role in controlling excitability in a number of systems, such as regulation of the contraction of smooth muscle, the tuning of hair cells in t [...] | Leucine rich repeat containing 26. | 0.695 |
KCNMA1 | TBCB | ENSSSCP00000032909 | ENSSSCP00000003151 | Calcium-activated potassium channel subunit alpha-1; Potassium channel activated by both membrane depolarization or increase in cytosolic Ca(2+) that mediates export of K(+). It is also activated by the concentration of cytosolic Mg(2+). Its activation dampens the excitatory events that elevate the cytosolic Ca(2+) concentration and/or depolarize the cell membrane. It therefore contributes to repolarization of the membrane potential. Plays a key role in controlling excitability in a number of systems, such as regulation of the contraction of smooth muscle, the tuning of hair cells in t [...] | Cytoskeleton-associated protein 1. | 0.632 |
KCNMB1 | KCNMA1 | ENSSSCP00000018017 | ENSSSCP00000032909 | Potassium calcium-activated channel subfamily M regulatory beta subunit 1. | Calcium-activated potassium channel subunit alpha-1; Potassium channel activated by both membrane depolarization or increase in cytosolic Ca(2+) that mediates export of K(+). It is also activated by the concentration of cytosolic Mg(2+). Its activation dampens the excitatory events that elevate the cytosolic Ca(2+) concentration and/or depolarize the cell membrane. It therefore contributes to repolarization of the membrane potential. Plays a key role in controlling excitability in a number of systems, such as regulation of the contraction of smooth muscle, the tuning of hair cells in t [...] | 0.807 |
KCNMB1 | KCNMB3 | ENSSSCP00000018017 | ENSSSCP00000027661 | Potassium calcium-activated channel subfamily M regulatory beta subunit 1. | Potassium calcium-activated channel subfamily M regulatory beta subunit 3; Belongs to the class-I aminoacyl-tRNA synthetase family. | 0.917 |
KCNMB1 | KCNMB4 | ENSSSCP00000018017 | ENSSSCP00000045790 | Potassium calcium-activated channel subfamily M regulatory beta subunit 1. | Potassium calcium-activated channel subfamily M regulatory beta subunit 4. | 0.956 |
KCNMB1 | KCNN3 | ENSSSCP00000018017 | ENSSSCP00000006973 | Potassium calcium-activated channel subfamily M regulatory beta subunit 1. | Small conductance calcium-activated potassium channel protein 3; Forms a voltage-independent potassium channel activated by intracellular calcium. Activation is followed by membrane hyperpolarization. Thought to regulate neuronal excitability by contributing to the slow component of synaptic afterhyperpolarization. The channel is blocked by apamin (By similarity). | 0.917 |
KCNMB1 | KCNN4 | ENSSSCP00000018017 | ENSSSCP00000003323 | Potassium calcium-activated channel subfamily M regulatory beta subunit 1. | Intermediate conductance calcium-activated potassium channel protein 4. | 0.932 |
KCNMB1 | LRRC26 | ENSSSCP00000018017 | ENSSSCP00000056401 | Potassium calcium-activated channel subfamily M regulatory beta subunit 1. | Leucine rich repeat containing 26. | 0.720 |
KCNMB3 | KCNMA1 | ENSSSCP00000027661 | ENSSSCP00000032909 | Potassium calcium-activated channel subfamily M regulatory beta subunit 3; Belongs to the class-I aminoacyl-tRNA synthetase family. | Calcium-activated potassium channel subunit alpha-1; Potassium channel activated by both membrane depolarization or increase in cytosolic Ca(2+) that mediates export of K(+). It is also activated by the concentration of cytosolic Mg(2+). Its activation dampens the excitatory events that elevate the cytosolic Ca(2+) concentration and/or depolarize the cell membrane. It therefore contributes to repolarization of the membrane potential. Plays a key role in controlling excitability in a number of systems, such as regulation of the contraction of smooth muscle, the tuning of hair cells in t [...] | 0.583 |