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The next version of STRING is ready for use in your analyses: updated networks across STRING newly available directed regulatory networks a new typed view showing functional, physical, and regulatory edges in one network new clustering options and cluster-based layouts … and much more!
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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ZNF518AZinc finger protein 518A isoform a. (1491 aa)    
Predicted Functional Partners:
U2SURP
U2 snRNP-associated SURP motif-containing protein isoform X2.
   
  
 0.795
THOC1
THO complex 1.
      
 0.773
CACNB3
Voltage-dependent L-type calcium channel subunit beta-3 isoform 1.
      
 0.670
BTAF1
B-TFIID TATA-box binding protein associated factor 1.
   
 
 0.607
ZCCHC2
Zinc finger CCHC domain-containing protein 2.
    
 
 0.598
PNISR
PNN interacting serine and arginine rich protein.
   
 
 0.571
PDE4D
Phosphodiesterase.
    
 
 0.554
PRPF39
Pre-mRNA processing factor 39.
      
 0.539
EPS8L1
EPS8 like 1.
    
 
 0.521
HMCES
Abasic site processing protein HMCES; Sensor of abasic sites in single-stranded DNA (ssDNA) required to preserve genome integrity by promoting error-free repair of abasic sites. Acts as an enzyme that recognizes and binds abasic sites in ssDNA at replication forks and chemically modifies the lesion by forming a covalent cross-link with DNA. The HMCES DNA-protein cross- link is then degraded by the proteasome. Promotes error-free repair of abasic sites by acting as a 'suicide' enzyme that is degraded, thereby protecting abasic sites from translesion synthesis (TLS) polymerases and endon [...]
      
 0.514
Your Current Organism:
Sus scrofa
NCBI taxonomy Id: 9823
Other names: S. scrofa, pig, pigs, swine, wild boar
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