STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SFXN2Sidoreflexin. (322 aa)    
Predicted Functional Partners:
C12orf73
Chromosome 12 open reading frame 73.
   
 
 0.732
RALGPS1
Ral GEF with PH domain and SH3 binding motif 1.
   
  
 0.724
MTBP
MDM2 binding protein.
    
 
 0.670
MTMR8
Myotubularin-related protein 8.
      
 0.663
PRRC2A
BAT2_N domain-containing protein.
      
 0.640
RNF14
RBR-type E3 ubiquitin transferase.
      
 0.623
DNAJB14
DnaJ heat shock protein family (Hsp40) member B14.
      
 0.622
COLQ
Collagen like tail subunit of asymmetric acetylcholinesterase.
      
 0.611
SFXN4
Sideroflexin 4.
  
 
 
0.587
EIF6
Eukaryotic translation initiation factor 6; Binds to the 60S ribosomal subunit and prevents its association with the 40S ribosomal subunit to form the 80S initiation complex in the cytoplasm. Behaves as a stimulatory translation initiation factor downstream insulin/growth factors. Is also involved in ribosome biogenesis. Associates with pre-60S subunits in the nucleus and is involved in its nuclear export. Cytoplasmic release of TIF6 from 60S subunits and nuclear relocalization is promoted by a RACK1 (RACK1)- dependent protein kinase C activity. In tissues responsive to insulin, contro [...]
   
  
 0.572
Your Current Organism:
Sus scrofa
NCBI taxonomy Id: 9823
Other names: S. scrofa, pig, pigs, swine, wild boar
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.