STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PNLIPPancreatic triacylglycerol lipase. (464 aa)    
Predicted Functional Partners:
CLPS
Colipase; Colipase is a cofactor of pancreatic lipase. It allows the lipase to anchor itself to the lipid-water interface. Without colipase the enzyme is washed off by bile salts, which have an inhibitory effect on the lipase.
   
 0.999
CEL
Carboxylic ester hydrolase; Belongs to the type-B carboxylesterase/lipase family.
   
 0.987
MGLL
Monoglyceride lipase.
     
 0.933
PNPLA2
Patatin-like phospholipase domain-containing protein 2 isoform X1.
   
 
 0.918
DGAT2
Uncharacterized protein.
     
 0.918
LPL
Lipoprotein lipase; Key enzyme in triglyceride metabolism. Catalyzes the hydrolysis of triglycerides from circulating chylomicrons and very low density lipoproteins (VLDL), and thereby plays an important role in lipid clearance from the blood stream, lipid utilization and storage. Mediates margination of triglyceride-rich lipoprotein particles in capillaries. Recruited to its site of action on the luminal surface of vascular endothelium by binding to GPIHBP1 and cell surface heparan sulfate proteoglycans; Belongs to the AB hydrolase superfamily. Lipase family.
     
0.910
DGAT1
Diacylglycerol O-acyltransferase 1; Belongs to the membrane-bound acyltransferase family.
     
 0.910
PNLIPRP1
Triacylglycerol lipase; Belongs to the AB hydrolase superfamily. Lipase family.
  
 
0.909
PNPLA3
Patatin like phospholipase domain containing 3.
     
 0.909
LIPC
Lipase C, hepatic type.
   
0.908
Your Current Organism:
Sus scrofa
NCBI taxonomy Id: 9823
Other names: S. scrofa, pig, pigs, swine, wild boar
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